This pictorial biography follows the life and times of the man who wrote some of the best known literature of the 20th century, from his birth in 1899 to his death in 1961.

Although shyness is a very common trait and almost everyone experiences it at some level, it’s often misunderstood. That’s because few of us ask about the frustration, anxiety, pain, and triumphs in the life of a shy person. These experiences remain hidden, and shy people may feel that nobody wants to know what’s going on in their hearts, minds, and souls. Their silence often isolates them. In Shyness: The Ultimate Teen Guide, Bernardo J. Carducci and Lisa Kaiser help young adults address a concern that millions of teens around the world experience. The authors emphasize that shyness is not a character flaw that needs to be cured, or that shy people need to remake their personalities and suddenly become extroverted. Instead, this book provides tips and strategies to help shy teens control their shyness by changing the thoughts, feelings, and behaviors that hold them back from reaching their true potential. Chapters in this book look at myths about shyness what makes people shy what it feels like to be shy how shyness affects identity how shy teens can meet people and make friends how shy people can tackle some of their biggest fears, like dating challenges beyond high school, such as leaving for college and developing a career Throughout this book, teens learn that the best-kept secret about shyness is that there’s nothing wrong with it. Designed to help readers understand and gain a greater appreciation for who they are, Shyness: The Ultimate Teen Guide will teach young adults—and those closest to them—what it means to be successfully shy.

Stevia rebaudiana is a remarkable South American plant that has become widely used in certain parts of the world as a natural sweetening agent and dietary supplement. Purified extracts of S. rebaudiana have been used as sweeteners and flavor enhancers in the food industry in Japan for over a quarter of a century, and have been found to be up to 300

This book addresses chemical and biological aspects related to sesquiterpene lactones (STLs). Experts in different fields have been invited to contribute on this class of compound's chemistry, isolation and identification, biological activities (antibacterial, antifungal, antiviral, antitrypanosomal, antileishmanial,antiplasmodial, antiproliferative and antiinflammatory), synthesis, biosynthesis, derivatization and QSAR analysis. Taxonomic and chemotaxonomic aspects related to the Asteraceae family are also contributed. The book begins by describing the chemical characteristics of STLs, their classification in different skeleton types, synthesis, distribution in nature and their most important biological properties. An overview of the group's main representatives, based on their importance for human health, as well as an update of the most recently isolated STLs, follow. The authors also provide an overview of the most common methods described in the literature for the extraction, purification, identification and structure elucidation of STLs, while also highlighting more recently developed methods. Furthermore, experts in the field provide an in-depth discussion of the most commonly employed in vitro and in vivo antiprotozoal assays against the different stages of parasites, as well as STLs' properties as anticancer agents in numerous cancer cell lines and animal models. Lastly, the book presents examples of the in vitro and in vivo activity of STLs and their mechanism of antiprotozoal action, together with an analysis of ultrastructural alterations, observed using TEM techniques. The book is aimed at scientists working on natural products: both those investigating this particular group of compounds and those who wish to further explore its potential as new drugs for medical conditions such as protozoal diseases and cancer.

What do the movements of molecules and the migration of humans have in common? How does the functionality of our brain tissue resemble the flow of traffic in New York City? How can understanding the spread of ideas, rumors, and languages help us tackle the spread a pandemic? This book provides an illuminating look into these seemingly disparate topics by exploring and expertly communicating the fundamental laws that govern the spreading and diffusion of objects. A collection of leading scientists in disciplines as diverse as epidemiology, linguistics, mathematics, and physics discuss various spreading phenomena relevant to their own fields, revealing astonishing similarities and correlations between the objects of study—be they people, particles, or pandemics. This updated and expanded second edition of an award-winning book introduces timely coverage of a subject with the greatest societal impact in recent memory—the global fight against COVID-19. Winner of the 2019 Literature Prize of the German Chemical Industry Fund and brainchild of the international and long-running Diffusion Fundamentals conference series, this book targets an interdisciplinary readership, featuring an introductory chapter that sets the stage for the topics discussed throughout. Each chapter provides ample opportunity to whet the appetite of those readers seeking a more in-depth treatment, making the book also useful as supplementary reading in appropriate courses dealing with complex systems, mass transfer, and network theory.

The Springer Handbook for Computational Intelligence is the first book covering the basics, the state-of-the-art and important applications of the dynamic and rapidly expanding discipline of computational intelligence. This comprehensive handbook makes readers familiar with a broad spectrum of approaches to solve various problems in science and technology. Possible approaches include, for example, those being inspired by biology, living organisms and animate systems. Content is organized in seven parts: foundations; fuzzy logic; rough sets; evolutionary computation; neural networks; swarm intelligence and hybrid computational intelligence systems. Each Part is supervised by its own Part Editor(s) so that high-quality content as well as completeness are assured.

The Mosaic of Autoimmunity: The Novel Factors of Autoimmune Diseases describes the multifactorial origin and diversity of expression of autoimmune diseases in humans. The term implies that different combinations of factors in autoimmunity produce varying and unique clinical pictures in a wide spectrum of autoimmune diseases. Most of the factors involved in autoimmunity can be categorized into four groups: genetic, immune defects, hormonal and environmental factors. In this book, the environmental factors are reviewed, including infectious agents, vaccines as triggers of autoimmunity, smoking and its relationship with rheumatoid arthritis, systemic lupus erythematosus, thyroid disease, multiple sclerosis and inflammatory bowel diseases. An entirely new syndrome, the autoimmune/inflammatory syndrome induced by adjuvants (ASIA), is also included, along with other diseases that are now recognized as having an autoimmune etiopathogenesis.

The authors start the book with overviews of the understanding and management of atopic dermatitis in conventional and Chinese medicine. They then review how atopic dermatitis was treated with herbal medicine and other Chinese medicine therapies in past eras, and highlight the treatments that continue to be used in contemporary clinical practice.The authors use evidence-based medicine principles and scientific techniques to review the current state of evidence from clinical studies of Chinese herbal medicine, acupuncture, and combinations of these therapies. Attention is given to studies evaluating these therapies used as an adjunct to conventional treatments. The authors summarise the results of analyses of clinical outcomes and discuss their implications for clinical practice of Chinese medicine and for future research.This book will inform clinicians and students of Chinese and integrative medicine of the current state of evidence from contemporary and traditional sources. Clinicians can refer to the herbal formulas and acupuncture treatments described in this book to make evidence-based decisions in patient care.The following features mark the importance of this book in the field:

"Smart and intelligent nanomaterials are currently in sharp focus in materials research as their properties are increasingly becoming more understood. This large and fairly comprehensive volume includes thirty chapters divided into four main areas: Inorganic materials, organic materials, composite materials, and biomaterials. It covers the latest research and developments in smart nanomaterials: processing, properties, and applications. Included are molecular device materials, biomimetic materials, hybrid-type functionalized polymers-composite materials, information-and energy-transfer materials, as well as environmentally friendly materials"--