Provides comprehensive coverage of laser-induced ionization processes for mass spectrometry analysis Drawing on the expertise of the leading academic and industrial research groups involved in the development of photoionization methods for mass spectrometry, this reference for analytical scientists covers both the theory and current applications of photo-induced ionization processes. It places widely used techniques such as MALDI side by side with more specialist approaches such as REMPI and RIMS, and discusses leading edge developments in ultrashort laser pulse desorption, to give readers a complete picture of the state of the technology. Photoionization and Photo-Induced Processes in Mass Spectrometry: Fundamentals and Applications starts with a complete overview of the fundamentals of the technique, covering the basics of the gas phase ionization as well as those of laser desorption and ablation, pulse photoionization, and single particle ionization. Numerous application examples from different analytical fields are described that showcase the power and the wide scope of photo ionization in mass spectrometry. -The first general reference book on photoionization techniques for mass spectrometry -Examines technologies and applications of gas phase resonance-enhanced multiphoton ionization mass spectrometry (REMPI-MS) and gas phase resonance ionization mass spectrometry (RIMS) -Provides complete coverage of popular techniques like MALDI -Discusses the current and potential applications of each technology, focusing on process and environmental analysis Photoionization and Photo-Induced Processes in Mass Spectrometry: Fundamentals and Applications is an excellent book for spectroscopists, analytical chemists, photochemists, physical chemists, and laser specialists.

The laser as a source of coherent optical radiation has made it possible to investigate nonlinear interaction of optical radiation with atoms and mole cules. Its availability has given rise to new research fields, such as non linear optics, laser spectroscopy, laser photochemistry, that lie at the boundary between quantum electronics and physical optics, optical spectros copy and photochemistry, respectively. The use of coherent optical radiation in each of these fields has led to the discovery of qualitatively ne\~ effects and possibilities; in particular, some rather subtle effects of interaction between highly monochromatic light and atoms and molecules, in optical spec troscopy, have formed the bases for certain methods of so-called nonlinear, laser Doppler-free spectroscopy. These methods have made it possible to in 5 6 crease the resolution of spectroscopic studies from between 10 and 10 , lim 11 ited by Doppl er 1 i ne broadeni ng up, to about 10 ; at present some 1 abor atories are developing new techniques that have even higher resolution. The discovery and elaboration of the methods of nonlinear laser spectroscopy have resulted largely from contributions by scientists from many countries, in particular from the USA (Massachusetts Institute of Technology, Stanford Uni versity, National Bureau of Standards in Boulder, Harvard University, etc. ), the USSR (P. N. Levedev Institute of Physics, Institute of Semiconductor Phys ics in Novosibirsk, Institute of Spectroscopy, etc.

Providing an exhaustive review of this topic, Inorganic Mass Spectrometry: Principles and Applications provides details on all aspects of inorganic mass spectrometry, from a historical overview of the topic to the principles and functions of mass separation and ion detection systems. Offering a comprehensive treatment of inorganic mass spectrometry, topics covered include: Recent developments in instrumentation Developing analytical techniques for measurements of trace and ultratrace impurities in different materials This broad textbook in inorganic mass spectrometry, presents the most important mass spectrometric techniques used in all fields of analytical chemistry. By covering recent developments and advances in all fields of inorganic mass spectrometry, this text provides researchers and students with information to answer any questions on this topic as well as providing the basic fundamentals for understanding this potentially complex, but increasingly relevant subject.

Fundamentals and Applications of Fourier Transform Mass Spectrometry is the first book to delve into the underlying principles on the topic and their linkage to industrial applications. Drs. Schmitt-Kopplin and Kanawati have brought together a team of leading experts in their respective fields to present this technique from many different perspectives, describing, at length, the pros and cons of FT-ICR and Orbitrap. Numerous examples help researchers decide which instruments to use for their particular scientific problem and which data analysis methods should be applied to get the most out of their data. - Covers FT-ICR-MS and Orbitrap's fundamentals, enhancing researcher knowledge - Includes details on ion sources, data processing, chemical analysis and imaging - Provides examples across the wide spectrum of applications, including omics, environmental, chemical, pharmaceutical and food analysis

Resonance Ionization Spectroscopy 1992 brings together developments in resonance ionization spectroscopy (RIS), an ultrasensitive analytical technique for elemental or isotopic analysis. The development of RIS in this book is of great interest to researchers in laboratories working in physics, chemistry, materials science, and earth and environmental sciences.

This thesis explores two distinct applications of laser spectroscopy: the study of nuclear ground state properties, and element selective radioactive ion beam production. It also presents the methods and results of an investigation into isotope shifts in the mercury isotopic chain. These Resonance Ionization Laser Ion Source (RILIS) developments are detailed, together with an RILIS ionization scheme that allowed laser ionized ion beams of chromium, germanium, radium and tellurium to be generated at the Isotope Mass Separator On-Line (ISOLDE) facility. A combination of laser spectroscopy with decay spectroscopy and mass spectrometry unambiguously demonstrated a cessation of the extreme shape staggering first observed in the 1970s and revealed the characteristic kink at the crossing of the N=126 shell closure. A series of RILIS developments were required to facilitate this experiment, including mercury "ionization scheme" development and the coupling of the RILIS with an arc discharge ion source. Laser spectroscopy has since become a powerful tool for nuclear physics and the Resonance Ionization Laser Ion Source (RILIS), of the ISOLDE facility at CERN, is a prime example. Highlighting important advances in this field, the thesis offers a unique and revealing resource. .

This work details an application of collinear resonance ionization spectroscopy for the separation of short-lived isomeric states and their subsequent study with decay spectroscopy. It reports the successful construction of a novel decay spectroscopy apparatus that can operate at pressures below 1 x 10^-9 mbar. The method is demonstrated by separating the nuclear ground and isomeric states of 204Fr and performing alpha-decay spectroscopy. An equivalent mass spectrometer would require 4.6 million times as much resolution to achieve the same result. This work unambiguously confirms the existence of a second isomeric state in 204Fr. The author also demonstrates the effectiveness of this method for laser spectroscopy and identification of hyperfine-structure components with energy tagging. This method was successfully used in 202Fr to identify ground and isomeric states. The measurement of 202Fr reported in this thesis demonstrates a factor of 100 improvement in sensitivity compared to state-of-the-art fluorescence techniques. The work reported in this thesis won the author the IOP Nuclear Physics Group Early Career Prize.

This monograph reviews all relevant technologies based on mass spectrometry that are used to study or screen biological interactions in general. Arranged in three parts, the text begins by reviewing techniques nowadays almost considered classical, such as affinity chromatography and ultrafiltration, as well as the latest techniques. The second part focusses on all MS-based methods for the study of interactions of proteins with all classes of biomolecules. Besides pull down-based approaches, this section also emphasizes the use of ion mobility MS, capture-compound approaches, chemical proteomics and interactomics. The third and final part discusses other important technologies frequently employed in interaction studies, such as biosensors and microarrays. For pharmaceutical, analytical, protein, environmental and biochemists, as well as those working in pharmaceutical and analytical laboratories.

Chemical Analysis of Food: Techniques and Applications reviews new technology and challenges in food analysis from multiple perspectives: a review of novel technologies being used in food analysis, an in-depth analysis of several specific approaches, and an examination of the most innovative applications and future trends. This book won a 2012 PROSE Award Honorable Mention in Chemistry and Physics from the Association of American Publishers. The book is structured in two parts: the first describes the role of the latest developments in analytical and bio-analytical techniques and the second reviews the most innovative applications and issues in food analysis. Each chapter is written by experts on the subject and is extensively referenced in order to serve as an effective resource for more detailed information. The techniques discussed range from the non-invasive and non-destructive, such as infrared spectroscopy and ultrasound, to emerging areas such as nanotechnology, biosensors and electronic noses and tongues. Important tools for problem-solving in chemical and biological analysis are discussed in detail. - Winner of a PROSE Award 2012, Book: Honorable Mention in Physical Sciences and Mathematics - Chemistry and Physics from the American Association of Publishers - Provides researchers with a single source for up-to-date information in food analysis - Single go-to reference for emerging techniques and technologies - Over 20 renowned international contributors - Broad coverage of many important techniques makes this reference useful for a range of food scientists

Laser Chemistry: Spectroscopy, Dynamics and Applications provides a basic introduction to the subject, written for students and other novices. It assumes little in the way of prior knowledge, and carefully guides the reader through the important theory and concepts whilst introducing key techniques and applications.