The very rapid pace of advances in biomedical research promises us a wide range of new drugs, medical devices, and clinical procedures. The extent to which these discoveries will benefit the public, however, depends in large part on the methods we choose for developing and testing them. Modern Methods of Clinical Investigation focuses on strategies for clinical evaluation and their role in uncovering the actual benefits and risks of medical innovation. Essays explore differences in our current systems for evaluating drugs, medical devices, and clinical procedures; health insurance databases as a tool for assessing treatment outcomes; the role of the medical profession, the Food and Drug Administration, and industry in stimulating the use of evaluative methods; and more. This book will be of special interest to policymakers, regulators, executives in the medical industry, clinical researchers, and physicians.

A wave of new health care innovation and growing demand for health care, coupled with uncertain productivity improvements, could severely challenge efforts to control future health care costs. A committee of the National Research Council and the Institute of Medicine organized a conference to examine key health care trends and their impact on medical innovation. The conference addressed the following question: In an environment of renewed concern about rising health care costs, where can public policy stimulate or remove disincentives to the development, adoption and diffusion of high-value innovation in diagnostics, therapeutics, and devices?

Advances in Medical and Surgical Engineering integrates the knowledge and experience of experts from academia and practicing surgeons working with patients. The cutting-edge progress in medical technology applications is making the traditional line between engineering and medical science ever thinner. This is an excellent resource for biomedical engineers working in industry and academia on developing medical technologies. It covers challenges in the application of technology in the clinic with views from an editorial team that is highly experienced in engineering, biomaterials, surgical practice, biomedical science and technology, and that has a proven track record of publishing applied biomedical science and technology. For medical practitioners, this book covers advances in technology in their domain. For students, this book identifies the opportunities of research based on the reviews of utilization of current technologies. The content in this book can also be of interest to policymakers, research funding agencies, and libraries, that are contributing to development of medical technologies. - Covers circulatory support, aortic valve implantation and microvascular antestmosis - Explores arthroplasty of both the knee and the shoulder - Includes tribology of materials, laser treatment and machining of biomaterial

The latest information on breakthroughs in allergies and respiratory conditions, brain health, cancer, cardiovascular disease, diabetes, digestive disorders, emotional health and much much more.

Surgery is a constantly evolving specialty in medicine – research and technological advances have made surgical procedures safer and more effective and offer shorter recovery times. Recent Advances in Surgery 39 is the latest volume in the annually-publishing series that reviews current topics in general surgery and its major subspecialties. Divided into eight sections, the book begins with topics of generic interest to surgeons, followed by discussion on subspecialty surgeries including upper and lower gastro-intestinal, hepato-pancreato-biliary, and vascular. This new volume features practical notes on surgical management conditions, advanced novel technologies such as radiotherapy techniques for LGI surgeries, and new developments including 3D printing in surgery. The final section describes clinical trials. With contributions from recognised experts, the majority from throughout the UK, this new volume covers all the latest developments in surgery, providing excellent revision material for professional examinations, and helping consultant surgeons keep up to date across the specialty. Key points Latest volume in series bringing postgraduates and surgeons up to date with the latest advances in general surgery and its subspecialties Features new developments such as 3D printing and advanced novel technologies Includes review of recent randomised clinical trials Recognised editor and author team, based mainly in the UK

Drawing on the work of the Roundtable on Evidence-Based Medicine, the 2007 IOM Annual Meeting assessed some of the rapidly occurring changes in health care related to new diagnostic and treatment tools, emerging genetic insights, the developments in information technology, and healthcare costs, and discussed the need for a stronger focus on evidence to ensure that the promise of scientific discovery and technological innovation is efficiently captured to provide the right care for the right patient at the right time. As new discoveries continue to expand the universe of medical interventions, treatments, and methods of care, the need for a more systematic approach to evidence development and application becomes increasingly critical. Without better information about the effectiveness of different treatment options, the resulting uncertainty can lead to the delivery of services that may be unnecessary, unproven, or even harmful. Improving the evidence-base for medicine holds great potential to increase the quality and efficiency of medical care. The Annual Meeting, held on October 8, 2007, brought together many of the nation's leading authorities on various aspects of the issues - both challenges and opportunities - to present their perspectives and engage in discussion with the IOM membership.

A current and cutting-edge reference, Current Therapy in Avian Medicine and Surgery takes the popular Current Therapy approach in providing succinct and clear information pertinent to the medical care of avian species. Most chapters include an up-to-date delivery of the current state of knowledge on their subject material, and provide practical approaches and thought processes applicable to diagnosis and therapy where appropriate. Information is always easy to find, with topics including the latest advances in internal medicine; behavioral medicine; anesthesia, analgesia, and surgery. Sections dedicated to welfare, conservation, and practice risk management explore important, but less commonly discussed aspects of avian practice; and the pattern recognition portion of the text offers readers a view of what companion bird conditions are likely to be seen in practice in different parts of the world. Written by a team of highly regarded contributors from around the world, this text helps readers, regardless of location and current knowledge, develop and augment skills in the medical and surgical care of avian species. The Current Therapy format provides current, up-to-date, succinct and clear information pertinent to the medical and surgical care of avian species. Coverage of clinically significant topics includes current veterinary scientific literature and hot topics relating to today's avian medicine and surgery. Coverage of a wide variety of bird species includes psittacines, pigeons, raptors, ratites, waterfowl, gallinaceous birds, and less common species. More than 800 full-color images show avian disease, management strategies and thought processes, and aid in formulating guidelines to care. World-renowned, expert contributors provide cutting-edge information, offering authoritative, accurate, and sometimes controversial opinions in many areas of study. Summary tables simplify the lookup of key facts and treatment guidelines. References in each chapter facilitate further reading and research on specific topics.

Nearly 20 million nuclear medicine procedures are carried out each year in the United States alone to diagnose and treat cancers, cardiovascular disease, and certain neurological disorders. Many of the advancements in nuclear medicine have been the result of research investments made during the past 50 years where these procedures are now a routine part of clinical care. Although nuclear medicine plays an important role in biomedical research and disease management, its promise is only beginning to be realized. Advancing Nuclear Medicine Through Innovation highlights the exciting emerging opportunities in nuclear medicine, which include assessing the efficacy of new drugs in development, individualizing treatment to the patient, and understanding the biology of human diseases. Health care and pharmaceutical professionals will be most interested in this book's examination of the challenges the field faces and its recommendations for ways to reduce these impediments.

v. 1. Research findings -- v. 2. Concepts and methodology -- v. 3. Implementation issues -- v. 4. Programs, tools and products.