Current applications and recent advances in genomics and proteomics Genomics and Proteomics Engineering in Medicine and Biology presents a well-rounded, interdisciplinary discussion of a topic that is at the cutting edge of both molecular biology and bioengineering. Compiling contributions by established experts, this book highlights up-to-date applications of biomedical informatics, as well as advancements in genomics-proteomics areas. Structures and algorithms are used to analyze genomic data and develop computational solutions for pathological understanding. Topics discussed include: Qualitative knowledge models Interpreting micro-array data Gene regulation bioinformatics Methods to analyze micro-array Cancer behavior and radiation therapy Error-control codes and the genome Complex life science multi-database queries Computational protein analysis Tumor and tumor suppressor proteins interactions

This book constitutes the refereed joint post-conference proceedings of the 6th International Symposium on High-Performance Computing, ISHPC 2005, held in, Japan, in 2005. It also includes the refereed post-proceedings of the First International Workshop on Advanced Low Power Systems 2006, ALPS2006, and some from the Workshop on Applications for PetaFLOPS Computing, APC 2005. A total of 42 papers were carefully selected from 76 submissions, covering a huge range of topics.

"Data Analysis" in the broadest sense is the general term for a field of activities of ever-increasing importance in a time called the information age. It covers new areas with such trendy labels as, e.g., data mining or web mining as well as traditional directions emphazising, e.g., classification or knowledge organization. Leading researchers in data analysis have contributed to this volume and delivered papers on aspects ranging from scientific modeling to practical application. They have devoted their latest contributions to a book edited to honor a colleague and friend, Hans-Hermann Bock, who has been active in this field for nearly thirty years.

Uncertainty Management in Information Systems: From Needs to Solutions is a book about how information systems can be made to manage information permeated with uncertainty. This subject is at the intersection of two areas of knowledge: information systems is an area that concentrates on the design of practical systems that can store and retrieve information; uncertainty modeling is an area in artificial intelligence concerned with accurate representation of uncertain information and with inference and decision-making under conditions infused with uncertainty. The first part of this book describes issues and challenges in the area of imperfect information that confront information systems, and the second part covers the principal theories for modeling imperfect information, and shows how these theories may be adapted to information systems. All chapters are original contributions and present solutions that have been applied and the experiences that have been gained from those solutions. The material has been closely edited by the book's editors for content, consistency and style. This authoritative book is state-of-the-art coverage of `Uncertainty Management in Information Systems'.

This volume aims to present recent advances in database technology from the viewpoint of the novel database paradigms proposed in the last decade. It focuses on the theory of the extended relational model and an example of an extended relational database programming language, Algres, is described. A free copy of Algres complements this work, and is available on the Internet. Audience: This work will be of interest to graduate students following advanced database courses, advanced data-oriented applications developers, and researchers in the field of database programming languages and software engineering who need a flexible prototyping platform for the development of software tools.

There is a growing interest in developing intelligent systems that would enable users to accomplish complex tasks in a Web-centric environment with relative ease by utilizing such technologies as intelligent agents, distributed computing and computer supported collaborative work. This book brings together researchers in related fields to explore various aspects of ISS design and implementation, as well as to share experiences and lessons learned in deploying intelligent support systems.

The major theme of this book is Intelligent Agents. An agent is a hardware or software system that is autonomous, interactive with and reactive to its environment and other agents. An agent can also be pro-active in taking the initiative in goal-directed behaviour. Intelligent Agents are one of the most important and exciting areas of research and development in computer science today.

Advances in web technology and the proliferation of sensors and mobile devices connected to the internet have resulted in the generation of immense data sets available on the web that need to be represented, saved, and exchanged. Massive data can be managed effectively and efficiently to support various problem-solving and decision-making techniques. Emerging Technologies and Applications in Data Processing and Management is a critical scholarly publication that examines the importance of data management strategies that coincide with advancements in web technologies. Highlighting topics such as geospatial coverages, data analysis, and keyword query, this book is ideal for professionals, researchers, academicians, data analysts, web developers, and web engineers.

Big data has always been a major challenge in geoinformatics as geospatial data come in various types and formats, new geospatial data are acquired very fast, and geospatial databases are inherently very large. And while there have been advances in hardware and software for handling big data, they often fall short of handling geospatial big data ef

The proliferation of massive data sets brings with it a series of special computational challenges. This "data avalanche" arises in a wide range of scientific and commercial applications. With advances in computer and information technologies, many of these challenges are beginning to be addressed by diverse inter-disciplinary groups, that indude computer scientists, mathematicians, statisticians and engineers, working in dose cooperation with application domain experts. High profile applications indude astrophysics, bio-technology, demographics, finance, geographi cal information systems, government, medicine, telecommunications, the environment and the internet. John R. Tucker of the Board on Mathe matical Seiences has stated: "My interest in this problern (Massive Data Sets) isthat I see it as the rnost irnportant cross-cutting problern for the rnathernatical sciences in practical problern solving for the next decade, because it is so pervasive. " The Handbook of Massive Data Sets is comprised of articles writ ten by experts on selected topics that deal with some major aspect of massive data sets. It contains chapters on information retrieval both in the internet and in the traditional sense, web crawlers, massive graphs, string processing, data compression, dustering methods, wavelets, op timization, external memory algorithms and data structures, the US national duster project, high performance computing, data warehouses, data cubes, semi-structured data, data squashing, data quality, billing in the large, fraud detection, and data processing in astrophysics, air pollution, biomolecular data, earth observation and the environment.