Includes the direct descents of every member and branch of the author's family.

Pure Mathematics for Advanced Level, Second Edition is written to meet the needs of the student studying for the General Certificate of Education at Advanced Level. The text is organized into 22 chapters. Chapters 1-5 cover topics in algebra such as operations with real numbers, the binomial theorem, and the quadratic function and the quadratic equation. The principles, methods and techniques in calculus, trigonometry, and co-ordinate geometry are provided as well. Two new chapters have been added: Numerical Methods and Vectors. Mathematics students will find this book extremely useful.

This book humorously chronicles the adventures and misadventures of a middle-aged guy from Chicago who cashes in his chips and moves to a so-called 'tropical island paradise'. There he holes up in a coconut wood, palm-thatched bungalow along the idyllic shores of an island in the Gulf of Siam. Please see web-site for synopsis, reviews and excerpts:morganmcfinn.com

FROM BEGINNING TO END Why "rituals"? My thinking was set in motion by those who, knowing I was a parish minister for many years, have asked me for advice about ceremonies and celebrations. They wanted words to use at graduations, funerals, and the welcoming of children. They inquired about grace at family meals, the reaffirmation of wedding vows, and ways to heal wounds suffered in personal conflict. People requested help with the rituals of solitude, such as meditation, prayer, and contemplation. . . . Rituals do not always involve words, occasions, officials, or an audience. Rituals are often silent, solitary, and self-contained. The most powerful rites of passage are reflective--when you look back on your life again and again, paying attention to the rivers you have crossed and the gates you have opened and walked on through, the thresholds you have passed over. I see ritual when people sit together silently by an open fire. Remembering. As human beings have remembered for thousands and thousands of years. FULGHUM

Discover how biomarkers can boost the success rate of drug development efforts As pharmaceutical companies struggle to improve the success rate and cost-effectiveness of the drug development process, biomarkers have emerged as a valuable tool. This book synthesizes and reviews the latest efforts to identify, develop, and integrate biomarkers as a key strategy in translational medicine and the drug development process. Filled with case studies, the book demonstrates how biomarkers can improve drug development timelines, lower costs, facilitate better compound selection, reduce late-stage attrition, and open the door to personalized medicine. Biomarkers in Drug Development is divided into eight parts: Part One offers an overview of biomarkers and their role in drug development. Part Two highlights important technologies to help researchers identify new biomarkers. Part Three examines the characterization and validation process for both drugs and diagnostics, and provides practical advice on appropriate statistical methods to ensure that biomarkers fulfill their intended purpose. Parts Four through Six examine the application of biomarkers in discovery, preclinical safety assessment, clinical trials, and translational medicine. Part Seven focuses on lessons learned and the practical aspects of implementing biomarkers in drug development programs. Part Eight explores future trends and issues, including data integration, personalized medicine, and ethical concerns. Each of the thirty-eight chapters was contributed by one or more leading experts, including scientists from biotechnology and pharmaceutical firms, academia, and the U.S. Food and Drug Administration. Their contributions offer pharmaceutical and clinical researchers the most up-to-date understanding of the strategies used for and applications of biomarkers in drug development.

Kang Hang was a Korean scholar-official taken prisoner in 1597 by an invading Japanese army during the Imjin War of 1592–1598. While in captivity in Japan, Kang recorded his thoughts on human civilization, war, and the enemy's culture and society, acting in effect as a spy for his king. Arranged and printed in the seventeenth century as Kanyangnok, or The Record of a Shepherd, Kang's writings were extremely valuable to his government, offering new perspective on a society few Koreans had encountered in 150 years and new information on Japanese politics, culture, and military organization. In this complete, annotated translation of Kanyangnok, Kang ruminates on human behavior and the nature of loyalty during a time of war. A neo-Confucianist with a deep knowledge of Chinese philosophy and history, Kang drew a distinct line between the Confucian values of his world, which distinguished self, family, king, and country, and a foreign culture that practiced invasion and capture, and, in his view, was largely incapable of civilization. Relating the experiences of a former official who played an exceptional role in wartime and the rare voice of a Korean speaking plainly and insightfully on war and captivity, this volume enables a deeper appreciation of the phenomenon of war at home and abroad.

Very successful when first performed in London in 1908, Diana of Dobson’s introduces its audience to the overworked and underpaid female assistants at Dobson’s Drapery Emporium, whose only alternative to their dead-end jobs is the unlikely prospect of marriage. Although Cicely Hamilton calls the play “a romantic comedy,” like George Bernard Shaw she also criticizes a social structure in which so-called self-made men profit from the cheap labour of others, and men with good educations, but insufficient inherited money, look for wealthy wives rather than for work. This Broadview edition also includes excerpts from Hamilton’s autobiography Life Errant (1935) and Marriage as a Trade (1909), her witty polemic on “the woman question”; historical documents illustrating employment options for women and women’s work in the theatre; and reviews of the original production of the play.