Serum lipoproteins and lipids were measured in 657 men (age 48) and were correlated with multiple constitutional and environmental variables. The two lipoprotein groups, Sf 0-12 and Sf 20-400, had a low intercorrelation and each correlated with different factors. The Sf 0-12 lipoproteins were related to constitutional obesity, cigarette smoking, and family history of vascular disease. The Sf 20-100 and Sf 100-400 lipoproteins were related to acquired obesity, carbohydrate tolerance, and 'aggressiveness' and 'sociability' as determined by personality survey. Carbohydrate tolerance, obesity, and personality were apparently independent variables. Serum triglyceride levels correlated with the same variables as the Sf 20-400 lipoproteins; serum cholesterol levels were related to factors that correlated with both lipoprotein groups. High levels (above 90th percentile) of each lipoprotein fraction and each lipid were associated with significantly greater quantities of the variables found to be correlated with each lipid fraction. The prevalence of familial hyperlipidemias was low (approximately 3-4%), but 18 per cent of individuals with elevated cholesterol and a high risk of coronary heart disease could be tentatively classified as having a type of familial hyperlipidemia. (Author).

This book provides an up-to-date review of the fundamentals of lipid metabolism and its role in cardiovascular diseases. Focusing on lipid transfer proteins in the circulation and cells, the role of important lipid transporters, the effect of recently discovered lipid binding proteins, and the link between lipid metabolism disorders and cardiovascular diseases, it covers phospholipid transfer protein, cholesteryl ester transfer protein, lipopolysaccharide binding protein, microsomal triglyceride transfer protein, ABC binding cassette members, and more. The book offers graduate students and researchers a coherent overview of lipid transfer and transport, as well as the limitations of current research in the field, and promotes further studies on cardiovascular diseases, as well as pharmaceutical research on drug discovery based on lipid transfer, transport, and binding.

Nutrition is unique in its behavioral approach--challenging students to actively participate, not just memorize the material. Offering a balanced coverage of behavioral change and the science of nutrition.

Diabetes mellitus has become epidemic on a global scale, and millions of new cases are diagnosed every year. The epidemic of diabetes mellitus is expected to result in one of the steepest rises in human morbidity and mortality ever observed outside of wartime. Insulin resistance is a hallmark of pre-diabetes and type 2 diabetes mellitus, and is characterized by impaired insulin-signaling transduction. Authoritative and comprehensive, Lipoproteins in Diabetes Mellitus details the many changes wrought by insulin resistance and diabetes mellitus on lipid and lipoprotein metabolism. The book begins by summarizing the various techniques to measure lipoproteins and their subclasses. The mechanisms by which insulin resistance and diabetes mellitus increase risk for atherosclerosis, diabetic retinopathy, and diabetic nephropathy are then explored in detail. Finally, the effects of lifestyle modification and the results of clinical trials using established and investigational drugs are discussed. An invaluable contribution to the literature, Lipoproteins in Diabetes Mellitus is a comprehensive reference on the clinical and scientific aspects of lipoproteins in diabetes. It will have a long-lasting and significant effect on the medical management of people with diabetes.

This concise, evidence-based resource covers all of today’s need-to-know information to quickly and effectively diagnose and manage common adolescent conditions...in an exceptionally user-friendly format. Because it’s so compact, clinically oriented, and easy to read, Adolescent Medicine: The Requisites in Pediatrics is an ideal study tool as well as a convenient reference for practice. Includes detailed discussions on special health issues, common medical problems, sexual and reproductive health, behavioral problems, and the transition to adult health care to help you gain a better understanding of the unique needs of the adolescent patient. Features a logical, consistent chapter format that helps you find the guidance you need quickly. Presents abundant tables, differential diagnoses, lab values/radiologic studies, treatment/therapy recommendations, and guidance on when to refer to a specialist equipping you for every clinical challenge. Discusses controversies concerning the standard of care with the aid of thought-provoking clinical scenarios to help you to determine the best course of action in difficult situations. Provides highlighted boxes that emphasize relevant case studies, key points of each section, and other important information making you aware of considerations that impact today’s practice. Uses a wealth of illustrations so you can see details more clearly.