At the crossroads of art and science, Beautiful Brain presents Nobel Laureate Santiago Ramón y Cajal’s contributions to neuroscience through his groundbreaking artistic brain imagery. Santiago Ramón y Cajal (1852–1934) was the father of modern neuroscience and an exceptional artist. He devoted his life to the anatomy of the brain, the body’s most complex and mysterious organ. His superhuman feats of visualization, based on fanatically precise techniques and countless hours at the microscope, resulted in some of the most remarkable illustrations in the history of science. Beautiful Brain presents a selection of his exquisite drawings of brain cells, brain regions, and neural circuits with accessible descriptive commentary. These drawings are explored from multiple perspectives: Larry W. Swanson describes Cajal’s contributions to neuroscience; Lyndel King and Eric Himmel explore his artistic roots and achievement; Eric A. Newman provides commentary on the drawings; and Janet M. Dubinsky describes contemporary neuroscience imaging techniques. This book is the companion to a traveling exhibition opening at the Weisman Art Museum in Minneapolis in February 2017, marking the first time that many of these works, which are housed at the Instituto Cajal in Madrid, have been seen outside of Spain. Beautiful Brain showcases Cajal’s contributions to neuroscience, explores his artistic roots and achievement, and looks at his work in relation to contemporary neuroscience imaging, appealing to general readers and professionals alike.

"Although physicians make use of science, this book argues that medicine is not itself a science, but rather an interpretive practice that relies heavily on clinical reasoning." "In How Doctors Think, Kathryn Montgomery contends that assuming medicine is strictly a science can have adverse effects. She suggests these can be significantly reduced by recognizing the vital role of clinical judgment."--BOOK JACKET.

Lab Girl is a book about work and about love, and the mountains that can be moved when those two things come together. It is told through Jahren's remarkable stories: about the discoveries she has made in her lab, as well as her struggle to get there; about her childhood playing in her father's laboratory; about how lab work became a sanctuary for both her heart and her hands; about Bill, the brilliant, wounded man who became her loyal colleague and best friend; about their field trips - sometimes authorised, sometimes very much not - that took them from the Midwest across the USA, to Norway and to Ireland, from the pale skies of North Pole to tropical Hawaii; and about her constant striving to do and be her best, and her unswerving dedication to her life's work. Visceral, intimate, gloriously candid and sometimes extremely funny, Jahren's descriptions of her work, her intense relationship with the plants, seeds and soil she studies, and her insights on nature enliven every page of this thrilling book. In Lab Girl, we see anew the complicated power of the natural world, and the power that can come from facing with bravery and conviction the challenge of discovering who you are.

Getting the right diagnosis is a key aspect of health care - it provides an explanation of a patient's health problem and informs subsequent health care decisions. The diagnostic process is a complex, collaborative activity that involves clinical reasoning and information gathering to determine a patient's health problem. According to Improving Diagnosis in Health Care, diagnostic errors-inaccurate or delayed diagnoses-persist throughout all settings of care and continue to harm an unacceptable number of patients. It is likely that most people will experience at least one diagnostic error in their lifetime, sometimes with devastating consequences. Diagnostic errors may cause harm to patients by preventing or delaying appropriate treatment, providing unnecessary or harmful treatment, or resulting in psychological or financial repercussions. The committee concluded that improving the diagnostic process is not only possible, but also represents a moral, professional, and public health imperative. Improving Diagnosis in Health Care, a continuation of the landmark Institute of Medicine reports To Err Is Human (2000) and Crossing the Quality Chasm (2001), finds that diagnosis-and, in particular, the occurrence of diagnostic errorsâ€"has been largely unappreciated in efforts to improve the quality and safety of health care. Without a dedicated focus on improving diagnosis, diagnostic errors will likely worsen as the delivery of health care and the diagnostic process continue to increase in complexity. Just as the diagnostic process is a collaborative activity, improving diagnosis will require collaboration and a widespread commitment to change among health care professionals, health care organizations, patients and their families, researchers, and policy makers. The recommendations of Improving Diagnosis in Health Care contribute to the growing momentum for change in this crucial area of health care quality and safety.

SHORTLISTED FOR THE ORWELL PRIZE FOR POLITICAL WRITING 2022 THE TIMES SCIENCE BOOK OF THE YEAR A GUARDIAN BEST POLITICS BOOK OF THE YEAR A TOP 5 SUNDAY TIMES BESTSELLER *Revised and updated edition with new chapter reflecting on the impact of Covid-19 two years on, and what come next* Did the UK government really 'follow the science' throughout the Covid-19 pandemic, as it claims? As head of the Wellcome Trust, Jeremy Farrar was one of the first people in the world to hear about a mysterious new disease in China - and to learn it could readily spread between people. A member of the SAGE emergency committee, Farrar was a key figure in both the UK and the World Health Organization at the onset of the Covid-19 pandemic amid great uncertainty, fast-moving situations and missed opportunities. Spike is his widely acclaimed inside story. His account casts light on the UK government's claims to be 'following the science' and is informed not just by Farrar's views but by interviews with other top scientists and political figures.

At the time of his death in 1995, Georges Canguilhem was a highly respected historian of science and medicine, whose engagement with questions of normality, the ideologization of scientific thought, and the conceptual history of biology had marked the thought of philosophers such as Michel Foucault, Louis Althusser, Pierre Bourdieu, and Gilles Deleuze. This collection of short, incisive, and highly accessible essays on the major concepts of modern medicine shows Canguilhem at the peak of his use of historical practice for philosophical engagement. In order to elaborate a philosophy of medicine, Canguilhem examines paramount problems such as the definition and uses of health, the decline of the Hippocratic understanding of nature, the experience of disease, the limits of psychology in medicine, myths and realities of therapeutic practices, the difference between cure and healing, the organism's self-regulation, and medical metaphors linking the organism to society. Writings on Medicine is at once an excellent introduction to Canguilhem's work and a forceful, insightful, and accessible engagement with elemental concepts in medicine. The book is certain to leave its imprint on anthropology, history, philosophy, bioethics, and the social studies of medicine.

An Independent Publisher Book Awards Gold Medal Winner A Progressive Book of the Year A TechCrunch Favorite Read of the Year “Deeply researched and thoughtful.” —Nature “An extended exercise in myth busting.” —Outside “A critique of both popular and scientific understandings of the hormone, and how they have been used to explain, or even defend, inequalities of power.” —The Observer Testosterone is a familiar villain, a ready culprit for everything from stock market crashes to the overrepresentation of men in prisons. But your testosterone level doesn’t actually predict your appetite for risk, sex drive, or athletic prowess. It isn’t the biological essence of manliness—in fact, it isn’t even a male sex hormone. So what is it, and how did we come to endow it with such superhuman powers? T’s story begins when scientists first went looking for the chemical essence of masculinity. Over time, it provided a handy rationale for countless behaviors—from the boorish to the enviable. Testosterone focuses on what T does in six domains: reproduction, aggression, risk-taking, power, sports, and parenting, addressing heated debates like whether high-testosterone athletes have a natural advantage as well as disagreements over what it means to be a man or woman. “This subtle, important book forces rethinking not just about one particular hormone but about the way the scientific process is embedded in social context.” —Robert M. Sapolsky, author of Behave “A beautifully written and important book. The authors present strong and persuasive arguments that demythologize and defetishize T as a molecule containing quasi-magical properties, or as exclusively related to masculinity and males.” —Los Angeles Review of Books “Provides fruitful ground for understanding what it means to be human, not as isolated physical bodies but as dynamic social beings.” —Science

A groundbreaking investigation of how inequality infects our minds and gets under our skin Why are people more relaxed and at ease with each other in some countries than others? Why do we worry so much about what others think of us and often feel social life is a stressful performance? Why is mental illness three times as common in the USA as in Germany? Why is the American dream more of a reality in Denmark than the USA? What makes child well-being so much worse in some countries than others? As The Inner Level demonstrates, the answer to all these is inequality. In The Spirit Level Richard Wilkinson and Kate Pickett put inequality at the center of public debate by showing conclusively that less equal societies fare worse than more equal ones across everything from education to life expectancy. The Inner Level now explains how inequality affects us individually, altering how we think, feel and behave. It sets out the overwhelming evidence that material inequities have powerful psychological effects: when the gap between rich and poor increases, so does the tendency to define and value ourselves and others in terms of superiority and inferiority. A deep well of data and analysis is drawn upon to empirically show, for example, that low social status leads to elevated levels of stress hormones, and how rates of anxiety, depression and addictions are intimately related to the inequality which makes that status paramount. Wilkinson and Pickett describe how these responses to hierarchies evolved, and why the impacts of inequality on us are so severe. In doing so, they challenge the conception that humans are inescapably competitive and self-interested. They undermine, too, the idea that inequality is the product of "natural" differences in individual ability. This book draws together many of the most urgent problems facing societies today, but it is not just an index of our ills. It demonstrates that societies based on fundamental equalities, sharing and reciprocity generate much higher levels of well-being, and lays out the path towards them.