When a young graduate student sat before Percival Bailey in 1960 and spoke of his longstanding interest in zoology and his recent interest in the nervous system, he asked the then Director of the Illinois Neuropsychiatric Institute if there was support in the scientific establishment for research in evolutionary comparative neurology. Bailey patted his abdomen with both hands and thought for a moment. Finally he said: "Young man, there is no place for people like you." The graduate student was crestfallen. To a large extent what Bailey said is still true. The greater part of research in neurobiology is directed toward answering a single broad question. How do brains in general, and the human brain in particular, work? This is a legitimate and important question. It is not, however, the only question worth answering. This overweening emphasis on function, especially in regard to the human nervous is a result of the origins of neurology in the clinic. The professional school, system, site of most such research, has been remarkably well-insulated from many of the major concerns of biology.

For a thorough study of the dynamics of particular brain compounds it is now possible to use and combine various molecular neuroanatomical methods (e.g. in situ hybridization, receptor localisation and immunocytochemistry) in a quantitative way on whole brain sections maintaining morphological details. Molecular Neuroanatomy deals with the many practical aspects and recent developments in these areas. The theoretical background of many techniques is presented, as well as clear, step-by-step instructions on the preparation and application of all the methods and techniques described in this book. It will be invaluable to all those working in the field of neuroscience. Available in both hardback and paperback, with colour illustrations.

2013 Reprint of 1960 Edition. Full facsimile of the original edition, not reproduced with Optical Recognition Software. By 1960, psychology had come to be dominated by behaviorism and learning theory, which emphasized the observable stimulus and response components of human and animal behavior while ignoring the cognitive processes that mediate the relationship between the stimulus and response. The cognitive phenomena occurring within the "black box" between stimulus and response were of little interest to behaviorists, as their mathematical models worked without them. In 1960, the book "Plans and the Structure of Behavior," authored by George A. Miller, Eugene Galanter, and Karl H. Pribram, was published. In this volume, Miller and his colleagues sought to unify the behaviorists' learning theory with a cognitive model of learned behavior. Whereas the behaviorists suggested that a simple reflex arc underlies the acquisition of the stimulus-response relationship, Miller and his colleagues proposed that "some mediating organization of experience is necessary" somewhere between the stimulus and response, in effect a cognitive process which must include monitoring devices that control the acquisition of the stimulus-response relationship. They named this fundamental unit of behavior the T.O.T.E. for "Test - Operate - Test - Exit."

This publication is intended to contribute to prevention and control of the morbidity and mortality associated with dengue and to serve as an authoritative reference source for health workers and researchers. These guidelines are not intended to replace national guidelines but to assist in the development of national or regional guidelines. They are expected to remain valid for five years (until 2014), although developments in research could change their validity.--Publisher's description.

With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.

Connecting the auditory brain stem to sensory, motor, and limbic systems, the inferior colliculus is a critical midbrain station for auditory processing. Winer and Schreiner's The Inferior Colliculus, a critical, comprehensive reference, presents the current knowledge of the inferior colliculus from a variety of perspectives, including anatomical, physiological, developmental, neurochemical, biophysical, neuroethological and clinical vantage points. Written by leading researchers in the field, the book is an ideal introduction to the inferior colliculus and central auditory processing for clinicians, otolaryngologists, graduate and postgraduate research workers in the auditory and other sensory-motor systems.