175 countries, four billion dollars, one scam: the thrilling rise and fall of the biggest cryptocurrency con in history and the woman behind it all In 2016, on stage at Wembley Arena in front of thousands of adoring fans, Dr. Ruja Ignatova promised her followers a financial revolution. The future, she said, belonged to cryptocurrencies such as Bitcoin. And the Oxford-educated, self-styled cryptoqueen vowed that she had invented the Bitcoin Killer. OneCoin would not only earn its investors untold fortunes; it would change the world. By March 2017, more than $4 billion had been invested in OneCoin in countries all around the world. But by October 2017, Ruja Ignatova had disappeared, and it slowly became clear that her revolutionary cryptocurrency was not all it seemed. Fortune was left asking, “Is OneCoin the biggest financial fraud in history?” In The Missing Cryptoqueen, acclaimed tech journalist Jamie Bartlett tells the story he began in his smash hit BBC podcast, entering the murky worlds of little-regulated cryptocurrencies and multilevel marketing schemes. Through a globe-crossing investigation into the criminal underworlds, corrupt governments, and the super-rich, he reveals a very modern tale of intrigue, techno-hype and herd madness that allowed OneCoin to become a million-person pyramid scheme—where, at the top, investors were making millions and, at the bottom, people were putting their livelihoods at risk. It’s the inside story of the smartest and biggest scam of the 21st Century—and the genius behind it, who is still on the run.

From the author of The Old Ways and Underland, an "eloquent (and compulsively readable) reminder that, though we're laying waste the world, nature still holds sway over much of the earth's surface." --Bill McKibben Winner of the Boardman Tasker Prize for Mountain Literature and a finalist for the Orion Book Award Are there any genuinely wild places left in Britain and Ireland? That is the question that Robert Macfarlane poses to himself as he embarks on a series of breathtaking journeys through some of the archipelago's most remarkable landscapes. He climbs, walks, and swims by day and spends his nights sleeping on cliff-tops and in ancient meadows and wildwoods. With elegance and passion he entwines history, memory, and landscape in a bewitching evocation of wildness and its vital importance.

Imagine you are a proud lesbian and a feminist. You have the odd doubt about your sexuality but you understand how the male-dominated world works and are angry about it. Then one day, a shock realisation occurs that not only are you not a lesbian, but you are in fact, a man. Your world is turned upside down. This is Charlie’s story.

This textbook focuses on the vascular biology and physiology that underlie vascular disorders in clinical medicine. Vascular biomedicine is a rapidly growing field as new molecular mechanisms of vascular health and disease are unraveled. Many of the major cardiovascular diseases including coronary artery disease, heart failure, stroke and vascular dementia are diseases of the vasculature. In addition vascular injury underpins conditions like kidney failure and cardiovascular complications of diabetes. This field is truly multidisciplinary involving scientists in many domains such as molecular and vascular biology, cardiovascular physiology and pharmacology and immunology and inflammation. Clinically, specialists across multiple disciplines are involved in the management of patients with vascular disorders, including cardiologists, nephrologists, endocrinologists, neurologists and vascular surgeons. This book covers a wide range of topics and provides an overview of the discipline of vascular biomedicine without aiming at in-depth reviews, but rather offering up-to-date knowledge organized in concise and structured chapters, with key points and pertinent references. The structure of the content provides an integrative and translational approach from basic science (e.g. stem cells) to clinical medicine (e.g. cardiovascular disease). The content of this book is targeted to those who are new in the field of vascular biology and vascular medicine and is ideal for medical students, graduate and postgraduate students, clinical fellows and academic clinicians with an interest in the vascular biology and physiology of cardiovascular disease and related pathologies.

In 1942, a lone five-year-old girl on a plane full of men from Bogota, Colombia landed at Croydon Aerodrome, London, England. Marta Lombard was that young girl, sent alone to start a new life.

This book brings together a group of leading economic historians to examine how institutions, innovation, and industrialization have determined the development of nations. Presented in honor of Joel Mokyr—arguably the preeminent economic historian of his generation—these wide-ranging essays address a host of core economic questions. What are the origins of markets? How do governments shape our economic fortunes? What role has entrepreneurship played in the rise and success of capitalism? Tackling these and other issues, the book looks at coercion and exchange in the markets of twelfth-century China, sovereign debt in the age of Philip II of Spain, the regulation of child labor in nineteenth-century Europe, meat provisioning in pre–Civil War New York, aircraft manufacturing before World War I, and more. The book also features an essay that surveys Mokyr's important contributions to the field of economic history, and an essay by Mokyr himself on the origins of the Industrial Revolution. In addition to the editors, the contributors are Gergely Baics, Hoyt Bleakley, Fabio Braggion, Joyce Burnette, Louis Cain, Mauricio Drelichman, Narly Dwarkasing, Joseph Ferrie, Noel Johnson, Eric Jones, Mark Koyama, Ralf Meisenzahl, Peter Meyer, Joel Mokyr, Lyndon Moore, Cormac Ó Gráda, Rick Szostak, Carolyn Tuttle, Karine van der Beek, Hans-Joachim Voth, and Simone Wegge.

This book aims to highlight the gaps and the transparency issues in the clinical research and trials processes and how there is a lack of information flowing back to researchers and patients involved in those trials. Lack of data transparency is an underlying theme within the clinical research world and causes issues of corruption, fraud, errors and a problem of reproducibility. Blockchain can prove to be a method to ensure a much more joined up and integrated approach to data sharing and improving patient outcomes. Surveys undertaken by creditable organisations in the healthcare industry are analysed in this book that show strong support for using blockchain technology regarding strengthening data security, interoperability and a range of beneficial use cases where mostly all respondents of the surveys believe blockchain will be important for the future of the healthcare industry. Another aspect considered in the book is the coming surge of healthcare wearables using Internet of Things (IoT) and the prediction that the current capacity of centralised networks will not cope with the demands of data storage. The benefits are great for clinical research, but will add more pressure to the transparency of clinical trials and how this is managed unless a secure mechanism like, blockchain is used.

Latin America’s economic performance is mediocre at best, despite abundant natural resources and flourishing neighbors to the north. The perplexing question of how some of the wealthiest nations in the world in the nineteenth century are now the most crisis-prone has long puzzled economists and historians. The Decline of Latin American Economies examines the reality behind the struggling economies of Argentina, Chile, and Mexico. A distinguished panel of experts argues here that slow growth, rampant protectionism, and rising inflation plagued Latin America for years, where corrupt institutions and political unrest undermined the financial outlook of already besieged economies. Tracing Latin America’s growth and decline through two centuries, this volume illustrates how a once-prosperous continent now lags behind. Of interest to scholars and policymakers alike, it offers new insight into the relationship between political systems and economic development.