Formulation And Delivery Of Proteins And Peptides
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Author |
: Chris Van Der Walle |
Publisher |
: Academic Press |
Total Pages |
: 381 |
Release |
: 2011-05-12 |
ISBN-10 |
: 9780123849366 |
ISBN-13 |
: 0123849365 |
Rating |
: 4/5 (66 Downloads) |
Synopsis Peptide and Protein Delivery by : Chris Van Der Walle
The growing area of peptide and protein therapeutics research is of paramount importance to medical application and advancement. A needed reference for entry level researchers and researchers working in interdisciplinary / collaborative projects, Peptide and Protein Delivery addresses the current and emerging routes for delivery of therapeutics. Covering cerebral delivery, pulmonary delivery, transdermal delivery, intestinal delivery, ocular delivery, parenteral delivery, and nasal delivery, this resource offers an overview of the main routes in therapeutics. Researchers across biochemistry, pharmaceutical, molecular biology, cell biology, immunology, chemistry and biotechnology fields will find this publication invaluable for peptide and protein laboratory research. - Discusses the most recent data, ideas and concepts - Presents case studies and an industrial perspective - Details information from the molecular level to bioprocessing - Thought provoking, for the novice to the specialist - Timely, for today's biopharmaceuticals market
Author |
: Eugene J. McNally |
Publisher |
: CRC Press |
Total Pages |
: 372 |
Release |
: 2007-10-26 |
ISBN-10 |
: 9780849379529 |
ISBN-13 |
: 0849379520 |
Rating |
: 4/5 (29 Downloads) |
Synopsis Protein Formulation and Delivery by : Eugene J. McNally
This title is intended to assist pharmaceutical scientists in the development of stable protein formulations during the early stages of the product development process, providing a comprehensive review of mechanisms and causes of protein instability in formulation development, coverage of accelerated stability testing methods and relevant analytica
Author |
: |
Publisher |
: |
Total Pages |
: 0 |
Release |
: 1994 |
ISBN-10 |
: OCLC:1132038025 |
ISBN-13 |
: |
Rating |
: 4/5 (25 Downloads) |
Synopsis Formulation and Delivery of Proteins and Peptides by :
Author |
: Ajay K. Banga |
Publisher |
: CRC Press |
Total Pages |
: 375 |
Release |
: 2005-09-14 |
ISBN-10 |
: 9781420039832 |
ISBN-13 |
: 1420039830 |
Rating |
: 4/5 (32 Downloads) |
Synopsis Therapeutic Peptides and Proteins by : Ajay K. Banga
Upon publication of the first edition of Therapeutic Peptides and Proteins ten years ago there were only 19 biotechology medicines on the market. Currently there are more than 100, with at least 400 more in various stages of development. That alone would be grounds for a new edition. Add to that the fact that it is still difficult to find up
Author |
: Lars Hovgaard |
Publisher |
: CRC Press |
Total Pages |
: 392 |
Release |
: 2012-11-14 |
ISBN-10 |
: 9781439853894 |
ISBN-13 |
: 1439853894 |
Rating |
: 4/5 (94 Downloads) |
Synopsis Pharmaceutical Formulation Development of Peptides and Proteins by : Lars Hovgaard
The rapid advances in recombinant DNA technology and the increasing availability of peptides and proteins with therapeutic potential are a challenge for pharmaceutical scientists who have to formulate these compounds as drug products. Pharmaceutical Formulation Development of Peptides and Proteins, Second Edition discusses the development of therap
Author |
: Ajay K. Banga |
Publisher |
: CRC Press |
Total Pages |
: 396 |
Release |
: 2015-04-23 |
ISBN-10 |
: 9781466566071 |
ISBN-13 |
: 1466566078 |
Rating |
: 4/5 (71 Downloads) |
Synopsis Therapeutic Peptides and Proteins by : Ajay K. Banga
There are more than 500 biopharmaceuticals on the market, including more than 200 therapeutic proteins, making biologics the fastest growing sector in the biopharmaceutical market. These products include more than 40 monoclonal antibodies, for indications ranging from treatment or mitigation of various types of cancer to rheumatoid arthritis. The c
Author |
: Lene Jorgensen |
Publisher |
: John Wiley & Sons |
Total Pages |
: 442 |
Release |
: 2009-10-23 |
ISBN-10 |
: 9780470688403 |
ISBN-13 |
: 0470688408 |
Rating |
: 4/5 (03 Downloads) |
Synopsis Delivery Technologies for Biopharmaceuticals by : Lene Jorgensen
Advances in biotechnology have provided scientists with an increasing number of biopharmaceuticals such as novel peptide and protein drugs as well as nucleic acid based drugs for gene therapy. However, successful delivery of these biopharmaceuticals is a major challenge because their molecular properties lead to poor physical and chemical stability in the body and limited membrane permeability. Therefore researchers are developing a range of new delivery technologies and materials to enable these new drugs to be delivered intact to their target sites. Delivery Technologies for Biopharmaceuticals describes strategies to overcome the main barriers for successful delivery of therapeutic peptides, proteins, and nucleic acid-based drugs or vaccines related to the site of administration and the target site. Many of the approaches described are reported in formulations in current clinical trials as well as in marketed products. Contents include: challenges in delivery of biopharmaceuticals novel formulation approaches for peptide and protein injectables non-viral chemical vectors and viral technology for delivery of nucleic acid based drugs immune response, adjuvants and delivery systems for vaccines several examples of delivery systems for different biopharmaceuticals a critical assessment of delivery technologies for biopharmaceuticals Delivery Technologies for Biopharmaceuticals is an essential single-volume introduction to the technologies used by researchers to ensure efficient delivery of this exciting new class of drugs. It will be of value to researchers and students working in drug delivery, formulation, biopharmaceuticals, medicinal chemistry, and new materials development.
Author |
: Zahra Shahrokh |
Publisher |
: |
Total Pages |
: 248 |
Release |
: 1997 |
ISBN-10 |
: UOM:39015041771521 |
ISBN-13 |
: |
Rating |
: 4/5 (21 Downloads) |
Synopsis Therapeutic Protein and Peptide Formulation and Delivery by : Zahra Shahrokh
This volume reviews protein stability and the analytical and biophysical characterization of proteins. It emphasizes drug delivery approaches, especially local delivery through the skin. Including both academic and industrial perspectives from such companies as Genentech, Amgen, and Merck, the book also discusses novel drug delivery polymers and the development of pharmaceutical protein formulations.
Author |
: Puneet Tyagi |
Publisher |
: Academic Press |
Total Pages |
: 318 |
Release |
: 2022-08-18 |
ISBN-10 |
: 9780128210604 |
ISBN-13 |
: 0128210605 |
Rating |
: 4/5 (04 Downloads) |
Synopsis Oral Delivery of Therapeutic Peptides and Proteins by : Puneet Tyagi
Oral Delivery of Therapeutic Peptides and Proteins provides a complete overview of the journey scientists pursue to attain protein and peptide oral delivery. The book highlights the physiological challenges that must be accounted for in addition to overcoming protease inhibition and acid stability issues that are commonly mentioned in this area of research. Primary topics include formulation technologies being adopted for oral delivery of proteins and peptides, modification of actives to make them more suited for oral delivery, animal models and their shortcomings in assessing oral bioavailability, and in vitro models to simulate drug absorption and transport. Academics and industry researchers working in formulation development and researchers and advanced students in biotechnology and pharmacy will find this a useful resource. Demonstrates how proteins and peptides transport throughout the gastrointestinal tract and how to evaluate their biological fate when encapsulated into certain delivery systems Examines developing technologies to improve future oral bioavailability Includes the in vitro and preclinical techniques needed for development
Author |
: Vincent Lee |
Publisher |
: CRC Press |
Total Pages |
: 913 |
Release |
: 2024-11-01 |
ISBN-10 |
: 9781040284568 |
ISBN-13 |
: 1040284566 |
Rating |
: 4/5 (68 Downloads) |
Synopsis Peptide and Protein Drug Delivery by : Vincent Lee
This reference/text covers fundamentals of peptide and protein drug delivery, including such considerations as synthesis, physical chemistry and biochemistry, analysis, proteolytic and transport constraints, pharmacokinetics, and pharmacodynamics; bioavailability from routes of administration, detai