This revision of the highly acclaimed Hayes' Handbook of Pesticide Toxicology is an in-depth, scientific sourcebook concerning use, properties, effects, and regulation of pesticides. This edition is a comprehensive examination by international experts from academia, government research, and the private sector of critical issues related to the need, use, and nature of chemicals used in modern pest management. This two-volume set contains up-to-date information on a broad range of topics which establishes context of pesticide use and outlines how they are scientifically evaluated. Experts from a variety of disciplines contribute to this work. Some provide a fresh look at existing information, and others look ahead at issues that are central to understanding pesticide use and toxicology in modern integrated pest management. Establishes a context for evaluation of pesticide use in agriculture, residential pest control and public health described Important discussion of strategies for pesticide risk assessment All major classes of pesticide considered Different routes of exposure critically evaluated Current regulatory issues defined Emerging issues concern topics of special relevance in the future Agents reviewed by experts from academia, government research, and the private sector

The Enzymes

Reviews of Environmental Contamination and Toxicology provides detailed review articles concerned with aspects of chemical contaminants, including pesticides, in the total environment with toxicological considerations and consequences.

Conteúdo: Hydrolosis: sulfate esters, carboxyl esters, glycosides; hydration.

Isozymes, I: Molecular Structure contains manuscripts presented at the Third International Conference on isozymes convened in April 1974 at Yale University. Separating 52 manuscripts into chapters, this book discusses the biology and biochemistry of isozymes. It also elucidates the multiple forms of mammalian DNA-dependent DNA polymerases, as well as RNA polymerases of maize, fungi, and Escherichia coli. Significant topics on some specific isozymes are given separately in other chapters.

During the past 60 years, the number of chemical disasters worldwide from military, occupational, and environmental sources has risen at an alarming rate. The profound controversy surrounding many chemicals makes objective analysis nearly impossible. Yet now more than ever -- with the daily exposure to a wide range of chemicals and the increased threat of chemical terrorism -- it is critical that we understand the role of chemicals in causing psychiatric illness. Unlike related books, this remarkable reference is intended specifically for psychiatric applications and is thus the definitive sourcebook for the many professionals called on to respond to these events. This work stands alone as the first on this topic to be written by a psychiatrist and the first to bring together the military, occupational, and environmental exposures causing psychiatric illness, including multiple chemical sensitivities, mass hysteria, radiation exposures, community stress reactions, and Gulf War and other syndromes. Unique highlights include A summary of the reported psychiatric symptoms attributed to each chemical class (chemical weapons, pesticides, fumigants, metals, solvents, gases, PCBs, Agent Orange, and other miscellaneous chemicals) in tables for easy reference. We use personal care products, take prescription drugs, pump gasoline, drink alcohol, and spray insecticides as part of our everyday lives. Yet rarely do we realize that significant exposures to the chemicals described in this book -- many of which we are exposed to in daily activities -- can damage the central nervous system, causing psychiatric illness. A comprehensive bibliography, in every chapter, of all the important material in English-language medical journals and books that has appeared on this subject since the late 19th century. These bibliographies cover everything from the first published reports of the dangers of carbon disulfide in the French rubber industry -- dangers that American medicine ignored for years -- through more recent large-scale chemical exposures that have serious long-term consequences. (e.g., Love Canal). The latest information about terrorist and military uses of chemical weapons -- of critical relevance in psychiatry today -- from World War I combatants exposed to chlorine, phosgene, mustard gas, arsenic, and cyanide to the first organophosphate, or nerve, gases (such as tabun and sarin) developed by the Germans before and during World War II (and used by Iraq in the Gulf War and by a religious cult in the terrorist subway attacks in Tokyo and Matsumoto, Japan). Quite simply, this book is a "must have" for psychiatric and medical professionals everywhere, with extended appeal among laypersons such as environmental/consumer advocates, attorneys, insurance professionals, industrial hygienists, disaster planners, and medical librarians.

Evaluates the carcinogenic risk to humans posed by Tobacco Smoking.

Pollutants, Human Health and the Environment is a comprehensive, up-to-date overview of environmental pollutants that are of current concern to human health. Clearly structured throughout, the main body of the book is divided by pollutant type with a chapter devoted to each group of pollutants. Each chapter follows a similar format to facilitate comparison and discussion. For each pollutant, the authors describe the sources, pathways, environmental fate and sinks as well as known toxicological effects. Importantly, the second chapter on heavy metals and other inorganic substances deals with trace element deficiencies which can have serious problems for human health. Some rocks and soils are naturally low in some trace elements and intensive agriculture over the past half century has effectively mined many trace elements reducing their levels in soils and crops. The final chapter is a discussion about the various risk assessment frameworks and regulations covering the main pollutants. Comprehensive, up-to-date coverage of environmental pollutants of concern to human health Clearly divided into pollutant type with each chapter devoted to a different pollutant group Clearly structured throughout with the same format for each chapter to help facilitate comparison and discussion and enable readers to prioritise chemicals of concern Description of the sources, pathways, environmental fate and known toxicological effect Includes contributions from leading researchers and edited by a team of experts in the field

The Handbook of Developmental Neurotoxicology provides a comprehensive account of the impacts, mechanisms, and clinical relevances of chemicals on the development of the nervous system. The book is written by internationally recognized experts on developmental neurotoxicology, covering subjects from basic neuro-development to toxic syndromes induced by various chemicals. It is an important text for both students and professionals who are interested in developmental neurobiology and neurotoxicology. - Written by internationally recognized experts on developmental neurotoxicology - Includes extensive references - Well illustrated with diagrams, charts and tables - Provides coverage of basic neurobiology as well as neurotoxicology