CMMI® for Development (CMMI-DEV) describes best practices for the development and maintenance of products and services across their lifecycle. By integrating essential bodies of knowledge, CMMI-DEV provides a single, comprehensive framework for organizations to assess their development and maintenance processes and improve performance. Already widely adopted throughout the world for disciplined, high-quality engineering, CMMI-DEV Version 1.3 now accommodates other modern approaches as well, including the use of Agile methods, Lean Six Sigma, and architecture-centric development. CMMI® for Development, Third Edition, is the definitive reference for CMMI-DEV Version 1.3. The authors have revised their tips, hints, and cross-references, which appear in the margins of the book, to help you better understand, apply, and find information about the content of each process area. The book includes new and updated perspectives on CMMI-DEV in which people influential in the model’s creation, development, and transition share brief but valuable insights. It also features four new case studies and five contributed essays with practical advice for adopting and using CMMI-DEV. This book is an essential resource–whether you are new to CMMI-DEV or are familiar with an earlier version–if you need to know about, evaluate, or put the latest version of the model into practice. The book is divided into three parts. Part One offers the broad view of CMMI-DEV, beginning with basic concepts of process improvement. It introduces the process areas, their components, and their relationships to each other. It describes effective paths to the adoption and use of CMMI-DEV for process improvement and benchmarking, all illuminated with fresh case studies and helpful essays. Part Two, the bulk of the book, details the generic goals and practices and the twenty-two process areas now comprising CMMI-DEV. The process areas are organized alphabetically by acronym for easy reference. Each process area includes goals, best practices, and examples. Part Three contains several useful resources, including CMMI-DEV-related references, acronym definitions, a glossary of terms, and an index.

As the generic pharmaceutical industry continues to grow and thrive, so does the need to conduct efficient and successful bioequivalence studies. In recent years, there have been significant changes to the statistical models for evaluating bioequivalence, and advances in the analytical technology used to detect drug and metabolite levels have made bioequivalence testing more difficult to conduct and summarize. The Handbook of Bioequivalence Testing offers a complete description of every aspect of bioequivalence testing. Features: Describes the current analytical methods used in bioequivalence testing, as well as their respective strengths and limitations Discusses worldwide regulatory requirements for filing for approval of generic drugs Covers GLP, GCP, and 21 CFR compliance requirements for qualifying studies for regulatory submission and facility certification Includes actual examples of reports approved by regulatory authorities to illustrate various scientific, regulatory, and formatting aspects Provides a list of vendors for the software used to analyze bioequivalence studies and recommendations Explains how to apply for a waiver, how to secure regulatory approval of reports, and how to obtain regulatory certification of facilities conducting bioequivalence studies

Introducing software evaluation; Process assessment; Product assessment; Practice and experience; Guide to global developments; Software and leagl liability; Standards, certification and the law; Appendices; Index.

Poultry products are universally popular and in recent years the consumption of poultry meat has risen dramatically. To ensure the continued growth and competitiveness of this industry, it is essential that poultry meat quality and safety are maintained during production and processing. This important collection provides an authoritative review of the key issues affecting poultry meat quality in production and processing.The book begins by establishing consumer requirements for meat quality, before examining the influence of breeding and husbandry, and techniques for stunning and slaughter of poultry. Chapters 5 and 6 look at primary and secondary processing and Chapters 7, 8 and 9 discuss packaging, refrigeration and other preservation techniques. There are also chapters on microbial hazards and chemical residues in poultry. Quality management issues are reviewed in the final group of chapters, including shelf-life and spoilage, measuring quality parameters and ways of maintaining safety and maximising quality.Poultry meat processing and quality is an essential reference book for technical managers in the Poultry Industry and anyone engaged in teaching or research on poultry meat production. - An essential reference for the entire poultry meat industry - Reviews the key issues affecting poultry meat quality in production and processing - Extensive analysis of poultry meat safety issues

Consideration of the interactions between decisions made at one point in the supply chain and its effects on the subsequent stages is the core concept of a systems approach. Postharvest Handling is unique in its application of this systems approach to the handling of fruits and vegetables, exploring multiple aspects of this important process through chapters written by experts from a variety of backgrounds.Newly updated and revised, this second edition includes coverage of the logistics of fresh produce from multiple perspectives, postharvest handing under varying weather conditions, quality control, changes in consumer eating habits and other factors key to successful postharvest handling.The ideal book for understanding the economic as well as physical impacts of postharvest handling decisions.Key Features:*Features contributions from leading experts providing a variety of perspectives*Updated with 12 new chapters*Focuses on application-based information for practical implementation*System approach is unique in the handling of fruits and vegetables

In the past several years, a revival of research devoted to nursing education has emerged. This emergence has changed the way many educators engage in their practice of working with learners; and learners have come to expect that they will have a rich learning experience designed to develop new (or enhance prior) knowledge, skills, and attitudes. The SAGE Handbook of Nursing Education provides a detailed map of the current discipline, with a carefully selected team of international contributors offering the latest thinking about education in nursing across key areas. This handbook will be a key resource for academic educators, as well as graduate and postgraduate learners.

Recent research into school effectiveness has corroborated the theory that the school leader plays a pivotal role making their school a successful institution, and is most often cited as the key factor in a school’s development. Reflecting the importance it is given in the today’s education landscape, this book explores the latest trends in school leadership from both theoretical and practical perspectives. Each chapter provides insight into an aspect of current research, with detailed case studies coming from as far afield as Hong Kong and Canada. In the context of the ever-increasing burden of responsibility placed on education management to safeguard and enhance the quality of education they provide, school leadership is now a core concern of policy makers. In addition, most countries are undertaking fundamental education reforms that will have a major influence on the nature of school leadership. Offering the most up-to-date research on this central issue, this book will both inform and shape the debate.

Work-based learning routes are a versatile and innovative way to gain higher education qualifications. This book reflects that flexibility and prepares tutors for helping work-based students learn in a variety of ways at both undergraduate and postgraduate level. Offering practical information and advice, the book covers the major aspects of work-based learning, which include: - Accreditation of prior learning (APL) - Work-based projects - Learning agreements - Relevant innovative assessment methods - Quality assurance and enhancement mechanisms - How technology can be utilised as a learning tool. Featuring activities, case studies and useful hints and tips informed by a range of international scholars, it's the ideal companion for tutors of work-based learning students.

Until now, research has given us only a limited understanding of how managers actually make sense of and apply management knowledge; how networks of interaction amongst managers help or hinder processes of knowledge diffusion and the sharing of best practice; and how these processes are all influenced both by the organisations in which managers act and by the professional communities of practice they belong to. Managing Modern Healthcare fills these important gaps in our understanding by drawing upon an in-depth study of management networks and practice in three healthcare organisations in the UK. It draws from the primary research a number of important and grounded lessons about how management networks develop and influence the spread of management knowledge and practice; how management training and development relates to the needs of managers facing challenging conditions; and how those conditions are themselves shaping the nature of management in healthcare. This book reveals how managers in practice are responding to the many contemporary challenges facing healthcare (and the NHS in particular) and how they are able or not to effectively exploit sources of knowledge, learning and best practice through the networks of practice they engage in to improve healthcare delivery and healthcare organisational performance. Managing Modern Healthcare makes a number of important theoretical contributions as well as practical recommendations. The theoretical and empirical contributions the book makes relate to wider work on networks and networking, management knowledge, situated learning/communities of practice, professionalization/professional identity and healthcare management more generally. The practical contribution comes in the form of recommendations for healthcare management practitioners and policy makers that are intended to impact upon and help enhance healthcare management delivery and performance.

Water Extraction of Bioactive Compounds: From Plants to Drug Development draws together the expert knowledge of researchers from around the world to outline the essential knowledge and techniques required to successfully extract bioactive compounds for further study. The book is a practical tool for medicinal chemists, biochemists, pharmaceutical scientists and academics working in the discovery and development of drugs from natural sources. The discovery and extraction of bioactive plant compounds from natural sources is of growing interest to drug developers, adding greater fuel to a simultaneous search for efficient, green technologies to support this. Particularly promising are aqueous based methods, as water is a cheap, safe and abundant solvent. Water Extraction of Bioactive Compounds: From Plants to Drug Development is a detailed guide to the fundamental concepts and considerations needed to successfully undertake such processes, supported by application examples and highlighting the most influential variables. Beginning with an introduction to plants as sources of drugs, the book highlights the need for a move towards both more rational and greener techniques in the field, and presents multiple innovative water-based strategies for the discovery and extraction of bioactive constituents of botanicals. A broad range of available techniques are reviewed, including conventional and pressurized hot water extraction techniques, intensified processes such as microwave-assisted, ultrasound-assisted processes, and enzyme assisted extraction, and processes using combined techniques. - Covers the theoretical background and range of techniques available to researchers, helping them to select the most appropriate extraction method for their needs - Presents up-to-date and cutting edge applications by international experts - Highlights current use and future potential for industrial scale applications - Offers a thorough introduction to plants as sources of drugs, highlighting strategies for the discovery of novel bioactive constituents of botanicals