Our intention has been to provide a short introduction to the chemistry and mode of action of insecticidal phosphoric acid compounds, with particular reference to the relationship between structure and activity. The yearly production of these pesticides is now approaching 100,000 tons and thus offers an important example of applied research. If, however, one examines the historical develop ment of these compounds, it is apparent that this was preceded by a hundred years of pure chemistry of phosphorus. The utility of the phosphoric acid pesticides is undisputed today - and furthermore it can be expected that they will solve many of the world's nutritional problems" yet from this field of applied research many paths are now leading back into basic research in chemistry, biochemistry, biology and toxicology etc. This clearly illustrates the problem of attempting to define pure and applied research. Originally, this book was conceived for students of chemistry who, on completion of their study, were uncertain about the place of applied research in industry but it was soon clear that such material, when supplemented with further data, would serve as an introduction to the field of pesticidal phosphoric acid compounds for many technicians, officials and scientists who, in various authorities in agriculture, in chemical and biological research, are concerned with the problems of crop protection and more recently with questions of pollution of the environ ment.

Pesticide control involves killing pest organisms or otherwise preventing them from destructive behavior. Pesticides are either natural or synthetic and are applied to target pests in a myriad of formulations (EC,WP, SP, FP, G etc.) and application technology systems (sprays, baits, slow-release diffusion, dust, etc.). In recent years, the bacterial genes coding for insecticidal proteins have been incorporated into various crops that dealt with the mortality of the pests feeding on them. Many other eco-friendly methods for insect pest control such as Integrated Pest Management (IPM), use of bio-pesticides etc., are becoming popular. Bio-pesticides and IPM should show good growth in the future, as there is growing concern for the eco-friendly organic agriculture and could be achieved through Good Agriculture Practices (GAP). Use of pesticides requires a proper understanding of the chemistry, their handling and their use in crop protection or hygiene. These are toxic chemicals and require a good understanding of therapy and antidotes at the time of poisoning. This e-book covers pesticide chemistry, metabolic/degradation pathways, biochemical toxicology, therapy and antidotes, nano-pesticides and terminologies associated with pesticide toxicology. the book should serve as a text book for academia, or as a reference work for agriculturists, environmentalists and industry professionals.

Resulting from the premier forum for pesticide development and use, this volume provides comprehensive coverage and even captures emerging technologies within the industry. All facets of pesticides are addressed here, including agriculture, agrochemicals, and environmental health aspects, as well as such global issues as food quality and safety.

Environmental-friendliness, issues of public health, and the pros and cons of genetically-modified crops all receive regular coverage in the world's media. This, in turn, has led to increased questioning and investigation of chemical pesticides. Stenersen's concise and timely introduction to chemical pesticides describes these compounds according to their mode of action at the cellular and biochemical level. Chemical Pesticides provides answers to questions such as why pesticides are toxic to the target organism and why pesticides are toxic to some organisms and not others. It describes how various poisons interfere with biochemical processes in organisms. The book also explores how resistance to pesticides develops, how resistance can be used to illustrate the theory of evolution, and how it can be used to produce herbicide-resistant crop plants. Legal matters and potential environmental problems are also discussed. By providing an integrated, yet simple description of modern chemical pesticides, the author provides a relevant text for professionals and students in biological disciplines such as biochemistry, medicine, agriculture, and veterinary science.

Many of the pesticides applied to food crops in this country are present in foods and may pose risks to human health. Current regulations are intended to protect the health of the general population by controlling pesticide use. This book explores whether the present regulatory approaches adequately protect infants and children, who may differ from adults in susceptibility and in dietary exposures to pesticide residues. The committee focuses on four major areas: Susceptibility: Are children more susceptible or less susceptible than adults to the effects of dietary exposure to pesticides? Exposure: What foods do infants and children eat, and which pesticides and how much of them are present in those foods? Is the current information on consumption and residues adequate to estimate exposure? Toxicity: Are toxicity tests in laboratory animals adequate to predict toxicity in human infants and children? Do the extent and type of toxicity of some chemicals vary by species and by age? Assessing risk: How is dietary exposure to pesticide residues associated with response? How can laboratory data on lifetime exposures of animals be used to derive meaningful estimates of risk to children? Does risk accumulate more rapidly during the early years of life? This book will be of interest to policymakers, administrators of research in the public and private sectors, toxicologists, pediatricians and other health professionals, and the pesticide industry.

This reference handbook provides fully updated chemical, regulatory, health, and safety information on nearly 800 pesticides and other agricultural chemicals. The clear, consistent and comprehensive presentation of information makes Sittig's an essential reference for a wide audience including first responders, environmental and industrial health/safety professionals, the food industry, the agricultural sector and toxicologists. Detailed profiles are provided for each substance listed, including: usage; crop-specific residue limits; hazard ratings for long-term human toxicity; and endocrine disruptor and reproductive toxicity information. Every chemical profile contains references and web links to source information from the EPA, OSHA, the World Health Organization (WHO), and other important advisory and lawmaking bodies. This work is focused on regulated chemicals. The substances covered include pesticides, insecticides, herbicides, fungicides, rodenticides and related agricultural chemicals used on foods grown and produced for both human and animal consumption. These products are organized with common names, chemical synonyms, trade names, chemical formulae, US EPA pesticide codes, EU regulations including Hazard Symbol and Risk Phrases, EINECS, RTECS, CAS, and other unique identifiers so that all who may have contact with, or interest in them can find needed information quickly. - A comprehensive reference for the agricultural sector, food industry, agrochemical manufacturing and distribution sector, and first responders - Brings together a wealth of hazard and response, regulatory and toxicological information in one convenient go-to handbook - Covers US, EU and worldwide regulatory requirements

This sweeping history reveals how the use of chemicals has saved lives, destroyed species, and radically changed our planet: “Remarkable . . . highly recommended.” —Choice In The Chemical Age, ecologist Frank A. von Hippel explores humanity’s long and uneasy coexistence with pests, and how the battles to exterminate them have shaped our modern world. He also tells the captivating story of the scientists who waged war on famine and disease with chemistry. Beginning with the potato blight tragedy of the 1840s, which led scientists on an urgent mission to prevent famine using pesticides, von Hippel traces the history of pesticide use to the 1960s, when Rachel Carson’s Silent Spring revealed that those same chemicals were insidiously damaging our health and driving species toward extinction. Telling the story in vivid detail, von Hippel showcases the thrills—and complex consequences—of scientific discovery. He describes the creation of chemicals used to kill pests—and people. And, finally, he shows how scientists turned those wartime chemicals on the landscape at a massive scale, prompting the vital environmental movement that continues today.

This book provides an overview of the major chemical aspects of pesticides giving detailed descriptions of the various groups of pesticides in current use - insecticides, acaricides, nematocides, rodenticides, fungicides and herbicides. The organic syntheses are discussed in detail, as are the biochemical aspects of the effectiveness and mechanisms of action of these chemical agents. The ecological aspects of the use of pesticides - nowadays an important consideration - are also discussed.The main trends of development in the field are also dealt with, e.g. the development of insecticides which present less of a threat to human beings and animals than the ones presently used, whose point of attack is the nervous system. Research is now concentrated on developing chemical compounds which affect the biochemistry or the special behavioural features of insects, instead of acting upon their nervous system. Newly discovered chemicals with selective action which are still in the developmental and experimentational stages are also described.Because of its comprehensive character, the book will be a useful source of information to those engaged in practical work in this field, as well as to researchers in the agricultural sciences.

This volume, with contributions from leading international experts, reports on the need to produce high quality food whilst satisfying environmental concerns. Including material on natural products, modes of action and metabolism, it covers all the key areas in pesticide chemistry and related activities. The contents outline the developments that have taken place in approaches to crop protection and our ability to develop complex, environmentally acceptable strategies for weed, pest and disease control.

Advances in Pesticide Science: Abstracts and Addendum documents the proceedings of the Fourth International Congress of Pesticide Chemistry held in Zurich on July 24-28, 1978. This book discusses the synthesis of isocoumarins and their biological activities; structure-activity correlations in control of membrane-bound linolenic acid with substituted pyridazinones; and oxidative processes in pesticide transformation. The cardiovascular and neurotoxicity of endosulfan; chemistry and plant growth regulating activity of fusicoccin derivatives and analogs; and pesticide interactions with naturally occurring food components are also elaborated. This compilation likewise covers the techniques for deriving realistic estimates of pesticide intakes; confirmation tests for pesticides based on gas chromatographic techniques; surfactants in flowable formulations; and thin-layer densitometry. This publication is a good reference for biologists and chemists researching on pesticides and its relation to food and the environment.