American public policy has had a long history of technological optimism. The success of the United States in research and development contributes to this optimism and leads many to assume that there is a technological fix for significant national problems. Since World War II the federal government has been the major supporter of commercial research and development efforts in a wide variety of industries. But how successful are these projects? And equally important, how do economic and policy factors influence performance and are these influences predictable and controllable? Linda Cohen, Roger Noll, and three other economists address these questions while focusing on the importance of R&D to the national economy. They examine the codependency between technological progress and economic growth and explain such matters as why the private sector often fails to fund commercially applicable research adequately and why the government should focus support on some industries and not others. They also analyze political incentives facing officials who enact and implement programs and the subsequent forces affecting decisions to continue, terminate, or redirect them. The central part of this book presents detailed case histories of six programs: the supersonic transport, communications satellites, the space shuttle, the breeder reactor, photovoltaics, and synthetic fuels. The authors conclude with recommendations for program restructuring to minimize the conflict between economic objectives and political constraints.

Accelerating the transition of new technologies into systems and products will be crucial to the Department of Defenses development of a lighter, more flexible fighting force. Current long transition times-ten years or more is now typical-are attributed to the complexity of the process. To help meet these challenges, the Department of Defense asked the National Research Council to examine lessons learned from rapid technology applications by integrated design and manufacturing groups. This report presents the results of that study, which was based on a workshop held to explore these successful cases. Three key areas emerged: creating a culture for innovation and rapid technology transition; methodologies and approaches; and enabling tools and databases.

Bridging the River of Hatred portrays the career of George Clifton Edwards, Jr., Detroit's visionary police commissioner whose efforts to bring racial equality, minority recruiting, and community policing to Detroit's police department in the early 1960s were met with much controversy within the city's administration. At a crucial time when the Civil Rights movement was gaining momentum and hostility between urban police forces and African Americans was close to eruption, Edwards chose solving racial and urban problems as his mission. Deeply committed to social justice, Edwards was a historical figure with vast political and legal experience, having served as head of the Detroit Housing Commission, a member of Detroit's common council, a juvenile court judge, a Michigan Supreme Court justice, and judge on the Sixth U.S. Circuit Court of Appeals. Incorporating material from a manuscript that Edwards wrote before his death, supplemented by historical research, Mary M. Stolberg provides a rare case study of problems in policing, the impoverishment of American cities, and the evolution of race relations during the turbulent 1960s.

What happens when you die? How does one transcend mankind to heavenly being, the known to the eternal mystery? One spring day in 1971, Calvin Cassady, a southwest Missouri teenager, was a victim in an unexplained automobile accident on a curvy Ozark mountain roadway. The impact caused the car that Calvin was a passenger in to burst into flames, plunging him into a clouded existence that included a walk through the valley of the shadow of death, leaving him on the threshold of eternal life. Eternity surrounded him and filled him with an absolute certainty of heaven. Standing before the Master and all his creation Calvin became troubled with the vision of his judgment and the life that he brought with him. Consumed with feelings of emptiness, he needed fulfillment. Bridging the Gap is the story of that miraculous event and the life of fulfillment that followed. Experience that fulfillment through Calvins spouse, his children, his students, his friends, and through the lives of total strangers as they became players in the great spiritual adventures of his life. Observe as the Holy Spirit guides Calvin through natural disasters and serious health issues, and feel the love as he takes into the mission field. Bridging the Gap celebrates the ordinary and illustrates the extraordinary results that occur during a lifetime lived for Christ. While you continue your spiritual journey, remember that faith, hope, and love conquer all. May your journey be fruitful, and may Gods peace be with you.

Overcoming technical risks requires demonstrating the soundness of a technical concept in a controlled setting and readying the product technology for the market. Topics include the extent to which purely technical risk is separable from market risk, how industrial managers make decisions on funding early-stage, high-risk technology projects, and how the government can and should act to reduce the technical risks so that firms will invest in them.

Drug repurposing is the development of existing drugs for new uses: given that 9 in 10 drugs that enter drug development are never marketed and therefore represent wasted effort, it is an attractive as well as inherently more efficient process. Three repurposed drugs can be brought to market for the same cost as one new chemical entity; and they can also be identified more quickly, an important benefit for patients whose diseases are progressing faster than therapeutic innovation. But repurposing also requires a fresh look at configuring pharmaceutical R&D, considering clinical, regulatory and patent issues much earlier than would otherwise be the case; a holistic gedanken experiment almost needs to be undertaken at the very start of any repurposing development. In addition to new ways of thinking, the discovery of repurposing opportunities can take advantage of artificial intelligence techniques to match the perfect new use for an existing drug. And while repurposing of medicines has been in the mind of every doctor since Hypocrates, modern clinical practice will simply have to adapt to new repurposing techniques in an age where the number of known diseases is increasing much faster than the healthcare dollars available.

Updated to include a new chapter about the influence of social media and the Internet—the 20th anniversary edition of Bowling Alone remains a seminal work of social analysis, and its examination of what happened to our sense of community remains more relevant than ever in today’s fractured America. Twenty years, ago, Robert D. Putnam made a seemingly simple observation: once we bowled in leagues, usually after work; but no longer. This seemingly small phenomenon symbolized a significant social change that became the basis of the acclaimed bestseller, Bowling Alone, which The Washington Post called “a very important book” and Putnam, “the de Tocqueville of our generation.” Bowling Alone surveyed in detail Americans’ changing behavior over the decades, showing how we had become increasingly disconnected from family, friends, neighbors, and social structures, whether it’s with the PTA, church, clubs, political parties, or bowling leagues. In the revised edition of his classic work, Putnam shows how our shrinking access to the “social capital” that is the reward of communal activity and community sharing still poses a serious threat to our civic and personal health, and how these consequences have a new resonance for our divided country today. He includes critical new material on the pervasive influence of social media and the internet, which has introduced previously unthinkable opportunities for social connection—as well as unprecedented levels of alienation and isolation. At the time of its publication, Putnam’s then-groundbreaking work showed how social bonds are the most powerful predictor of life satisfaction, and how the loss of social capital is felt in critical ways, acting as a strong predictor of crime rates and other measures of neighborhood quality of life, and affecting our health in other ways. While the ways in which we connect, or become disconnected, have changed over the decades, his central argument remains as powerful and urgent as ever: mending our frayed social capital is key to preserving the very fabric of our society.

This “comforting…thoughtful” (The Washington Post) guide to maintaining a high quality of life—from resilient old age to the first inklings of a serious illness to the final breath—by the New York Times bestselling author of Knocking on Heaven’s Door is a “roadmap to the end that combines medical, practical, and spiritual guidance” (The Boston Globe). “A common sense path to define what a ‘good’ death looks like” (USA TODAY), The Art of Dying Well is about living as well as possible for as long as possible and adapting successfully to change. Packed with extraordinarily helpful insights and inspiring true stories, award-winning journalist Katy Butler shows how to thrive in later life (even when coping with a chronic medical condition), how to get the best from our health system, and how to make your own “good death” more likely. Butler explains how to successfully age in place, why to pick a younger doctor and how to have an honest conversation with them, when not to call 911, and how to make your death a sacred rite of passage rather than a medical event. This handbook of preparations—practical, communal, physical, and spiritual—will help you make the most of your remaining time, be it decades, years, or months. Based on Butler’s experience caring for aging parents, and hundreds of interviews with people who have successfully navigated our fragmented health system and helped their loved ones have good deaths, The Art of Dying Well also draws on the expertise of national leaders in family medicine, palliative care, geriatrics, oncology, and hospice. This “empowering guide clearly outlines the steps necessary to prepare for a beautiful death without fear” (Shelf Awareness).

The SBIR program allocates 2.5 percent of 11 federal agencies' extramural R&D budgets to fund R&D projects by small businesses, providing approximately $2 billion annually in competitive awards. At the request of Congress, the National Academies conducted a comprehensive study of how the SBIR program has stimulated technological innovation and used small businesses to meet federal research and development needs. Drawing substantially on new data collection, this report provides a comprehensive overview of the SBIR program at the five agencies representing 96 percent of program expenditure-DOD, NIH, NSF, DOE, and NASA-and makes recommendations on improvements to the program. Separate books on each agency will also be issued.

An expert exploration of the foundations of America’s science and technology policies, and the dynamics of its innovation system. Why study science and technology policy? What role does innovation play, and how do we foster it? Economics tells us technological innovation drives economic growth and societal well-being, but technology is always a double-edged sword—great technological advances offer both opportunities and threats. In Pioneering Progress, William Bonvillian explains the complex science and technology innovation system and discusses the challenges of emerging industrial policies. Drawing on in-depth case studies on critical areas such as energy, computing, advanced manufacturing, and health, with an emphasis on the needed public policy and the federal government R&D role in those systems, Bonvillian reviews the foundations of economic growth theory, innovation systems theory, and innovation organization theory. Bonvillian, a highly respected expert who has worked as a deputy assistant secretary of transportation in the federal government and a senior advisor in Congress, reviews a new theory of direct and indirect economic factors in the innovation system. He describes the innovation-based competitive and advanced manufacturing challenges now facing the US economy, reviews comparative efforts in other nations, studies the varied models for how federal science and technology mission agencies are organized, and explores the growth of public-private partnership and industrial policy models as a way for science mission agencies to pursue mission agendas. Pioneering Progress places particular emphasis on the organization and role of medical science and energy innovation agencies and how we can address the gaps in the health, energy, and advanced production innovation economic models.