BOOKER PRIZE–WINNING AUTHOR Set in a world in which the Reformation failed, this award-winning science fiction tale is “one of the best . . . alternate-worlds novels in existence” (Philip K. Dick) In Kingsley Amis’s virtuoso foray into virtual history it is 1976, but the modern world is a medieval relic, frozen in intellectual and spiritual time ever since Martin Luther was promoted to pope back in the sixteenth century. Stephen the Third, the king of England, has just died, and Mass (Mozart’s second requiem) is about to be sung to lay him to rest. In the choir is our hero, Hubert Anvil, an extremely ordinary ten-year-old boy with a faultless voice. In the audience is a select group of experts whose job is to determine whether that faultless voice should be preserved by performing a certain operation. Art, after all, is worth any sacrifice. How Hubert realizes what lies in store for him and how he deals with the whirlpool of piety, menace, terror, and passion that he soon finds himself in are the subject of a classic piece of counterfactual fiction equal to Philip K. Dick’s The Man in the High Castle. The Alteration won the John W. Campbell Memorial Award for best science-fiction novel in 1976.

It has been recognized for more than a thousand years that the function of the brain, like the function of the other organs of the body, is determined by its physical, chemical, and biological properties. Evidence that even its highest functions could be explained by these properties was gathered only in recent years, however; these findings, which clearly have to be confirmed by a great deal of further experimental evidence, indicate that most, if not all, of the functions of the brain are based on its bio chemical and biophysical mechanisms. This at first hearing may sound rather simple, but the ability to understand learning, emotion, perhaps even creativity, on biological terms may well be the most important scientific discovery of all time. Few pieces of knowledge can influence our future health and well-being to the degree that understanding of mental mechanisms will. It has been clearly shown in many ways in the previous volumes of this Handbook that from the biochemical or neurochemical point of view the brain is one of the most active organs. The brain seems stable and in some respects permanent; this is evidence not of inactivity but of carefully controlled homeostasis, of dynamic rather than static equilibrium, with most components undergoing metabolic alterations.

Special edition of the Federal Register, containing a codification of documents of general applicability and future effect ... with ancillaries.

Special edition of the Federal register, containing a codification of documents of general applicability and future effect as of ... with ancillaries.