Understanding Cancer from a Systems Biology Point of View: From Observation to Theory and Back starts with a basic question, why do we sometimes observe accelerated metastatic growth after resection of primary tumors? Next, it helps readers understand the systemic nature of cancer and how it affects treatment approaches and decisions. The book puts together aspects of cancer that many readers have most likely never combined, using unfamiliar, novel methods. It is a valuable resource for cancer researchers, cancer biologists, mathematicians and members of the biomedical field who are interested in applying systems biology methodologies for understanding and treating cancer. Explains the systemic nature of cancer and how it affects decisions on treatment Brings a variety of methods together, showing, in detail, the logical approach to finding answers to complex questions Discusses the theoretical underpinnings of cancer as a systemic disease, providing the reader with valuable information on applicable cases

Enhancing Surgical Performance: A Primer in Non-Technical Skills explains why non-technical skills are vital for safe and effective performance in the operating theatre. The book provides a full account, with supporting empirical evidence, of the Non-Technical Skills for Surgeons (NOTSS) system and behavioural rating framework, which helps identify

The first edition of Robotic Surgery was written only a decade after the introduction of robotic technology. It was the first comprehensive robotic surgery reference and represented the early pioneering look ahead to the future of surgery. Building upon its success, this successor edition serves as a complete multi-specialty sourcebook for robotic surgery. It seeks to explore an in-depth look into surgical robotics and remote technologies leading to the goal of achieving the benefits of traditional surgery with the least disruption to the normal functions of the human body. Written by experts in the field, chapters cover the fundamental principles of robotic surgery and provide clear instruction on their clinical application and long term results. Most notably, one chapter on “The Blueprint for the Establishment of a Successful Robotic Surgery Program: Lessons from Admiral Hymen R. Rickover and the Nuclear Navy” outlines the many valuable lessons from the transformative change which was brought about by the introduction of nuclear technology into the conventional navy with Safety as the singular goal of the change process. Robotics represents a monumental triumph of surgical technology. Undoubtedly, the safety of the patient will be the ultimate determinant of its success. The second edition of Robotic Surgery aims to erase the artificial boundaries of specialization based on regional anatomy and serves as a comprehensive multispecialty reference for all robot surgeons. It allows them to contemplate crossing boundaries which are historically defined by traditional open surgery.

Operating theatres are very private workplaces. There have been few research investigations into how highly trained doctors and nurses work together to achieve safe and efficient anaesthesia and surgery. While there have been major advances in surgical and anaesthetic procedures, there are still significant risks for patients during operations and adverse events are not unknown. Due to rising concern about patient safety, surgeons and anaesthetists have looked for ways of minimising adverse events. Behavioural scientists have been encouraged by clinicians to bring research techniques used in other industries into the operating theatre in order to study the behaviour of surgeons, nurses and anaesthetists. Safer Surgery presents one of the first collections of studies designed to understand the factors influencing safe and efficient surgical, anaesthetic and nursing practice. The book is written by psychologists, surgeons and anaesthetists, whose contributions combine to offer readers the latest research techniques and findings from some of the leading investigators in this field. It is designed for practitioners and researchers interested in understanding the behaviour of operating theatre team members, with a view to enhancing both training and practice. The material is also suitable for those studying behaviour in other areas of healthcare or in high-risk work settings. The aims of the book are to: a) present the latest research on the behaviour of operating theatre teams b) describe the techniques being used by psychologists and clinicians to study surgeons, anaesthetists and theatre nurses' task performance c) outline the safety implications of the research to date.

This new addition to the popular Essentials series provides a broad, general introduction to the topic of simulation within clinical education. An ideal tool for both teaching and learning, Essential Simulation in Clinical Education provides a theoretical and practical introduction to the subject of simulation, whilst also offering strategies for successful use of simulators within general clinical education and demonstrating best practice throughout. This timely new title provides: The latest information on developments in the field, all supported by an evidence-base Content written by a global team of experts Discussion of policy and strategy initiatives to ground simulation within the healthcare context Practical examples of cases, including inter-professional learning. A superb companion for those involved in multi-disciplinary healthcare teaching, or interested in health care education practices, Essential Simulation in Clinical Education is the most comprehensive guide to the field currently available.

This reference places the latest information at users' fingertips, and a more streamlined format makes it easy to find the exact information quickly and conveniently. Includes access to a companion Web site for additional resources.

Posttraumatic stress disorder (PTSD) is a common and disabling condition that often goes undiagnosed for years, and even when the diagnosis is made, treatment is frequently ineffective, especially for combat veterans. Cognitive behavioural therapy with imaginal exposure is considered first-line treatment, but many cannot or will not engage in imaginal exposure, which is not surprising, since avoidance of reminders of the trauma is a defining feature of PTSD. Novel technologies offer an alternative to facilitate exposure therapy, through virtual reality (VR). This book outlines state-of-the-art approaches to improving the diagnosis and treatment of PTSD, with a particular emphasis on the promise and pitfalls associated with VR exposure therapy. The world’s leading experts in this cutting edge field describe their VR work in phobias and other mental disorders, and chart a course for future studies to improve the diagnosis and treatment of PTSD.

Rutherford's Vascular Surgery - the most acclaimed comprehensive reference in its field - presents definitive, state-of-the-art guidance on every aspect of vascular health care, equipping you to make the best clinical decisions and optimize outcomes. Extensively revised by many new, international authors - led by Drs. Jack Cronenwett and K. Wayne Johnston - and now published in association with the Society for Vascular Surgery, this 7th Edition provides the authoritative answers that surgeons, interventionalists, and vascular medicine specialists need to provide effective care for vascular surgery patients. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you’re using or where you’re located. Get answers you can depend on. Now published in association with the Society for Vascular Surgery, Rutherford's delivers the world’s most trusted information on all major areas of vascular health care, written by international experts, with up-to-date bibliographies and annotated recommended references. Overcome any clinical challenge with in-depth sections on Fundamental Considerations, Patient Evaluation, Atherosclerotic Risk Factors, Perioperative Care, Bleeding and Clotting, Complications, Venous Disease, Lymphedema, Arteriovenous Anomalies, Hemodialysis Access, Miscellaneous Technique, Grafts and Devices, Cerebrovascular Disease, Lower Extremity Arterial Disease, Upper Extremity Arterial Disease, Arterial Aneurysms, Renal and Mesenteric Disease, and Trauma and Acute Limb Ischemia. Choose the best management option for each patient with discussions of operative, endovascular, and non-operative approaches for vascular conditions. Access the complete contents of Rutherford's Vascular Surgery online at www.expertconsult.com - with monthly updates from the Journal of Vascular Surgery and the European Journal of Vascular and Endovascular Surgery, plus videos of procedures, an image library, review questions, and more. Master the latest developments, techniques, and approaches with thorough updates on endovascular applications, vascular access, imaging, non-operative management, and much more. View clinical and physical findings and operative techniques more vividly with a new full-color layout and more full-color images.