MicroRNAs (miRNAs) are RNA molecules, conserved by evolution, that regulate gene expressions and their recent discovery is revolutionising both basic biomedical research and drug discovery. Expression levels of MiRNAs have been found to vary between tissues and with developmental stages and hence evaluation of the global expression of miRNAs potentially provides opportunities to identify regulatory points for many different biological processes. This wide-ranging reference work, written by leading experts from both academia and industry, will be an invaluable resource for all those wishing to use miRNA techniques in their own research, from graduate students, post-docs and researchers in academia to those working in R&D in biotechnology and pharmaceutical companies who need to understand this emerging technology. From the discovery of miRNAs and their functions to their detection and role in disease biology, this volume uniquely integrates the basic science with industry application towards drug validation, diagnostic and therapeutic development. Forewords by: Sidney Altman, Yale University, Winner of the Nobel Prize in Chemistry, 1989 and Victor R. Ambros, Dartmouth Medical School, Co-discoverer of MicroRNAs

This revolutionary and best-selling resource contains more than 200 pages of additional information and expanded discussions on zeolites, bitumen, conducting polymers, polymerization reactors, dendrites, self-assembling nanomaterials, atomic force microscopy, and polymer processing. This exceptional text offers extensive listings of laboratory exercises and demonstrations, web resources, and new applications for in-depth analysis of synthetic, natural, organometallic, and inorganic polymers. Special sections discuss human genome and protonics, recycling codes and solid waste, optical fibers, self-assembly, combinatorial chemistry, and smart and conductive materials.

A beautiful book that reveals the world of art collecting from home, featuring exquisite examples of Hollingsworth and Morris family furniture. Start with House, Finish with a Collection is the story of how a couple's use of American art and antiques evolved from furnishing a house into a full-blown passion for collecting. Featuring exquisite examples of Hollingsworth and Morris family furniture, Weber boxes, Pennsylvania clocks and Kirk-Stieff silver, as well as American paintings by the Peale family, Edward Hicks, Edward Redfield and Horace Pippin, this museum-calibre collection reveals a pride in the early American sensibility. The combination of text and extraordinary photographs traces this remarkable journey and demonstrates that life can be more than comfortable living among these collections. The compendium catalogues the diversified and important collection, making this a valuable scholarly reference as well as a reading pleasure.

Covering the most important pathogens of potatoes, this handbook provides clear, concise descriptions of the symptoms and cycles of diseases. It also provides detail on the distribution, economic importance, and advice on the control. Illustrated with over 250 color photographs of affected crops, pest profiles and detailed characteristics of common prey to potato crops, this book is the ultimate aid to the rapid identification and control of disease for this important crop. * Coverage includes identifcation, disease cycle, economic importance, and control * Problem-oriented organization * Over 250 color illustrations; full color * Field guide practicality

Planetary scientist and educator Ken Coles has teamed up with Ken Tanaka from the United States Geological Survey's Astrogeology team, and Phil Christensen, Principal Investigator of the Mars Odyssey orbiter's THEMIS science team, to produce this all-purpose reference atlas, The Atlas of Mars. Each of the thirty standard charts includes: a full-page color topographic map at 1:10,000,000 scale, a THEMIS daytime infrared map at the same scale with features labeled, a simplified geologic map of the corresponding area, and a section describing prominent features of interest. The Atlas is rounded out with extensive material on Mars' global characteristics, regional geography and geology, a glossary of terms, and an indexed gazetteer of up-to-date Martian feature names and nomenclature. This is an essential guide for a broad readership of academics, students, amateur astronomers, and space enthusiasts, replacing the NASA atlas from the 1970s.